Immunomodulatory effects and mechanisms of distraction osteogenesis

S Yang, N Wang, Y Ma, S Guo, S Guo… - International Journal of …, 2022 - nature.com
Distraction osteogenesis (DO) is widely used for bone tissue engineering technology.
Immune regulations play important roles in the process of DO like other bone regeneration …

Endothelial progenitor cell‐derived extracellular vesicles: a novel candidate for regenerative medicine and disease treatment

Z Xing, C Zhao, H Liu, Y Fan - Advanced healthcare materials, 2020 - Wiley Online Library
Extracellular vesicles (EVs) are a heterogeneous group of membranous structures, which
can be secreted by most cell types. As a product of paracrine secretion, EVs are considered …

Exosomes secreted by endothelial progenitor cells accelerate bone regeneration during distraction osteogenesis by stimulating angiogenesis

Y Jia, Y Zhu, S Qiu, J Xu, Y Chai - Stem cell research & therapy, 2019 - Springer
Background Distraction osteogenesis (DO) is an effective but lengthy procedure to fully
induce bone regeneration in large bone defects. Accumulating evidence supports the role of …

[HTML][HTML] CXCL12/CXCR4 signaling and other recruitment and homing pathways in fracture repair

C Yellowley - BoneKEy reports, 2013 - ncbi.nlm.nih.gov
Cell recruitment, migration and homing to the fracture site are essential for the inflammatory
process, neovascularization, chondrogenesis, osteogenesis and ultimately bone …

Calcitonin gene-related peptide enhances distraction osteogenesis by increasing angiogenesis

J Mi, J Xu, H Yao, X Li, W Tong, Y Li, B Dai… - … Engineering Part A, 2021 - liebertpub.com
Distraction osteogenesis (DO) is a well-established surgical technique for treating bone
defect and limb lengthening. The major drawback of DO is the long treatment period as the …

[HTML][HTML] ECFC-derived exosomal THBS1 mediates angiogenesis and osteogenesis in distraction osteogenesis via the PI3K/AKT/ERK pathway

F Liao, Z Liao, T Zhang, W Jiang, P Zhu, Z Zhao… - Journal of Orthopaedic …, 2022 - Elsevier
Background Distraction osteogenesis (DO) is a widely used bone regenerative technique.
However, the DO process is slow, and the consolidation phase is long. Therefore, it is of …

Human fetal mesenchymal stem cell secretome enhances bone consolidation in distraction osteogenesis

J Xu, B Wang, Y Sun, T Wu, Y Liu, J Zhang… - Stem cell research & …, 2016 - Springer
Background Distraction osteogenesis (DO) is one of the most dramatic reconstructive
techniques for inducing bone regeneration, but it involves an undesirably long period for …

Efficacy and safety of unilateral tibial cortex transverse transport on bilateral diabetic foot ulcers: a propensity score matching study

W Qin, X Nie, H Su, Y Ding, L He, K Liu, J Hou… - Journal of Orthopaedic …, 2023 - Elsevier
Abstract Background Tibial Cortex Transverse Transport (TTT) has been demonstrated to be
an effective treatment for unilateral diabetic foot ulcers (UDFUs). However, this retrospective …

Strontium doped mesoporous silica nanoparticles accelerate osteogenesis and angiogenesis in distraction osteogenesis by activation of Wnt pathway

X Liu, Y Sun, J Shen, HS Min, J Xu, Y Chai - … : Nanotechnology, Biology and …, 2022 - Elsevier
Distraction osteogenesis (DO) is a powerful method to reconstruct segmented bone defects
in the extremities. However, the main shortcoming of DO is the time-consuming …

Total flavonoids of rhizoma drynariae enhances angiogenic-osteogenic coupling during distraction osteogenesis by promoting type H vessel formation through PDGF …

Z Shen, Z Chen, Z Li, Y Zhang, T Jiang, H Lin… - Frontiers in …, 2020 - frontiersin.org
Background: Total flavonoids of Rhizoma Drynariae (TFRD), extracted from the kidney-
tonifying traditional Chinese medicine Rhizoma Rrynariae, has been proved to be effective …