Mining filarial genomes for diagnostic and therapeutic targets
S Bennuru, EM O'Connell, PM Drame, TB Nutman - Trends in parasitology, 2018 - cell.com
Filarial infections of humans cause some of the most important neglected tropical diseases.
The global efforts for eliminating filarial infections by mass drug administration programs …
The global efforts for eliminating filarial infections by mass drug administration programs …
Identification and prioritisation of potential vaccine candidates using subtractive proteomics and designing of a multi-epitope vaccine against Wuchereria bancrofti
M Aarthy, GN Pandiyan, R Paramasivan, A Kumar… - Scientific Reports, 2024 - nature.com
This study employed subtractive proteomics and immunoinformatics to analyze the
Wuchereria bancrofti proteome and identify potential therapeutic targets, with a focus on …
Wuchereria bancrofti proteome and identify potential therapeutic targets, with a focus on …
The epitome of novel techniques and targeting approaches in drug delivery for treating lymphatic filariasis
Background: Lymphatic filariasis is a pervasive and life-threatening disease for human
beings. Currently, 893 million people in 49 countries worldwide affected by lymphatic …
beings. Currently, 893 million people in 49 countries worldwide affected by lymphatic …
Essential proteins and possible therapeutic targets of Wolbachia endosymbiont and development of FiloBase-a comprehensive drug target database for Lymphatic …
OP Sharma, MS Kumar - Scientific Reports, 2016 - nature.com
Lymphatic filariasis (Lf) is one of the oldest and most debilitating tropical diseases. Millions
of people are suffering from this prevalent disease. It is estimated to infect over 120 million …
of people are suffering from this prevalent disease. It is estimated to infect over 120 million …
Virtual screening of traditional Chinese medicine (TCM) database: identification of fragment-like lead molecules for filariasis target asparaginyl-tRNA synthetase
Lymphatic filariasis (LF) is a vector borne infectious disease caused by the nematode
Wuchereria bancrofti, Brugia malayi, and Brugia timori. Over 120 million people are affected …
Wuchereria bancrofti, Brugia malayi, and Brugia timori. Over 120 million people are affected …
Prevalence of lymphatic filariasis in a tea garden worker population of Dibrugarh (Assam), India after six rounds of mass drug administration
AM Khan, P Dutta, CK Sarmah, NK Baruah… - Journal of Vector …, 2015 - journals.lww.com
Methods: Finger prick thick blood smears (20 mm 3) were made from individuals aged≥ 2 yr
old during night blood survey in between 2000-0000 hrs during the period of November …
old during night blood survey in between 2000-0000 hrs during the period of November …
Modelling studies determing the mode of action of anthelmintics inhibiting in vitro trehalose-6-phosphate phosphatase (TPP) of Anisakis simplex sl
E Łopieńska-Biernat, T Molcan, Ł Paukszto… - Experimental …, 2018 - Elsevier
Abstract The trehalose-6-phosphate phosphatase (TPP) enzyme is involved in the synthesis
of trehalose, the main sugar in the energy metabolism of nematodes. TPP is a member of the …
of trehalose, the main sugar in the energy metabolism of nematodes. TPP is a member of the …
[HTML][HTML] In silico characterization of a RNA binding protein of cattle filarial parasite Setaria digitata
N Nagaratnam, EH Karunanayake, KH Tennekoon… - …, 2014 - ncbi.nlm.nih.gov
Human lymphatic filariasis (HLF) is a neglected tropical disease which threatens nearly 1.4
billion people in 73 countries worldwide. Wuchereria bancrofti is the major causative agent …
billion people in 73 countries worldwide. Wuchereria bancrofti is the major causative agent …
Molecular cloning, purification and characterization of Brugia malayi phosphoglycerate kinase
R Kumar, PK Doharey, JK Saxena, S Rathaur - Protein Expression and …, 2017 - Elsevier
Phosphoglycerate kinase (PGK) is a glycolytic enzyme present in many parasites. It has
been reported as a candidate molecule for drug and vaccine developments. In the present …
been reported as a candidate molecule for drug and vaccine developments. In the present …
[PDF][PDF] Lymphatic filariasis: drug targets and nematicidal plants
N Anil, VR Talluri - Journal of Pharmaceutical Sciences and …, 2015 - academia.edu
Lymphatic filariasis (LF), a mosquito-borne disease, is caused by the parasitic filarial
nematodes (roundworms) Wuchereria bancrofti (W. bancrofti), Brugia malayi (B. malayi), or …
nematodes (roundworms) Wuchereria bancrofti (W. bancrofti), Brugia malayi (B. malayi), or …