A celebrated and controversial hypothesis suggests that some biological systems—parts,
aspects, or groups of them—may extract important functional benefits from operating at the …

A widely discussed hypothesis in neuroscience is that transiently active ensembles of
neurons, known as" cell assemblies," underlie numerous operations of the brain, from …

In the past decade, the cell-type specific connectivity and activity of local cortical networks
have been characterized experimentally to some detail. In parallel, modeling has been …

Although short-term plasticity is believed to play a fundamental role in cortical computation,
empirical evidence bearing on its role during behavior is scarce. Here we looked for the …

Most synaptic inputs are made onto the dendritic tree. Recent work has shown that dendrites
play an active role in transforming synaptic input into neuronal output and in defining the …

Autism spectrum disorders (ASD) are neurodevelopmental disorders, that are characterized
by core symptoms, such as alterations of social communication and restrictive or repetitive …

Homosynaptic Hebbian-type plasticity provides a cellular mechanism of learning and
refinement of connectivity during development in a variety of biological systems. In this …

A neuroscientific perspective on the mind–body problem that focuses on how the brain
actually accomplishes mental causation. The issues of mental causation, consciousness …

Short-term plasticity (STP) denotes changes in synaptic strength that last up to tens of
seconds. It is generally thought that STP impacts information transfer across synaptic …

Numerous experimental data suggest that simultaneously or sequentially activated
assemblies of neurons play a key role in the storage and computational use of long-term …