Combination antiretroviral therapy (ART) can block multiple stages of the HIV-1 life cycle to
prevent progression to AIDS in people living with HIV-1. However, owing to the persistence …

NKG2D is an activating receptor expressed by all NK cells and subsets of T cells. It serves
as a major recognition receptor for detection and elimination of transformed and infected …

HIV is difficult to eradicate due to the persistence of a long-lived reservoir of latently infected
cells. Previous studies have shown that natural killer cells are important to inhibiting HIV …

Natural killer group 2, member D (NKG2D) is an activating receptor present on the surface of
natural killer (NK) cells, some NKT cells, CD8+ cytotoxic T cells, γδ T cells, and under certain …

Natural killer (NK) cells have an important role in the control of viral infections, recognizing
virally infected cells through a variety of activating and inhibitory receptors,,. Epidemiological …

Abstract The Natural Killer Group 2D (NKG2D) receptor plays an important role in protecting
the host from infections and cancer. By recognizing ligands induced on infected or tumor …

Natural killer (NK) cells are cytotoxic effector cells that target and lyse virally infected cells;
many viruses therefore encode mechanisms to escape such NK cell killing. Here, we …

The HIV protein, Vpr, is a multifunctional accessory protein critical for efficient viral infection
of target CD4+ T cells and macrophages. Vpr is incorporated into virions and functions to …

Since the first reports of AIDS, skin involvement has become a burdensome stigma for
seropositive patients and a challenging task for dermatologist and infectious disease …

Natural killer (NK) cell degranulation in response to virus-infected cells is triggered by
interactions between invariant NK cell surface receptors and their ligands on target cells …