PURPOSE OF REVIEW This article summarizes the cognitive and behavioral functions of
the prefrontal cortex with an emphasis on executive cognitive functions and the clinical …

Abstract Major Depressive Disorder (MDD) is one of the most common and debilitating
mental disorders; however, its etiology remains unclear. This paper aims to summarize the …

Psilocybin is a serotonergic psychedelic with untapped therapeutic potential. There are hints
that the use of psychedelics can produce neural adaptations, although the extent and …

The advent of neuroimaging has increased our understanding of brain function. While most
brain-wide functional imaging modalities exploit neurovascular coupling to map brain …

Damage to specific brain circuits can cause specific neuropsychiatric symptoms.
Therapeutic stimulation to these same circuits may modulate these symptoms. To determine …

Biomarkers have transformed modern medicine but remain largely elusive in psychiatry,
partly because there is a weak correspondence between diagnostic labels and their …

Objective: Imaging studies of major depressive disorder have reported structural and
functional abnormalities in a variety of spatially diverse brain regions. Quantitative meta …

Psychedelics have inspired new hope for treating brain disorders, as they seem to be unlike
any treatments currently available. Not only do they produce sustained therapeutic effects …

Major depression is a highly prevalent condition, affecting approximately 10% of the
population. 1 It is also a growing global problem, 2 and has been consistently associated …

Bipolar disorder (BD) is a leading cause of worldwide disability among mood disorders.
Pathological mechanisms are still vastly unclear, and current treatments with conventional …