As a data-driven science, genomics largely utilizes machine learning to capture dependencies in data and derive novel biological hypotheses. However, the ability to extract …
T Ching, DS Himmelstein… - Journal of the …, 2018 - royalsocietypublishing.org
Deep learning describes a class of machine learning algorithms that are capable of combining raw inputs into layers of intermediate features. These algorithms have recently …
S Min, B Lee, S Yoon - Briefings in bioinformatics, 2017 - academic.oup.com
In the era of big data, transformation of biomedical big data into valuable knowledge has been one of the most important challenges in bioinformatics. Deep learning has advanced …
Over the past decade, polypharmacy instances have been common in multi-diseases treatment. However, unwanted drug-drug interactions (DDIs) that might cause unexpected …
Increases in throughput and installed base of biomedical research equipment led to a massive accumulation of-omics data known to be highly variable, high-dimensional, and …
It is critical, but difficult, to catch the small variation in genomic or other kinds of data that differentiates phenotypes or categories. A plethora of data is available, but the information …
S Ekins - Pharmaceutical research, 2016 - Springer
Over the past decade we have witnessed the increasing sophistication of machine learning algorithms applied in daily use from internet searches, voice recognition, social network …
Z Zhang, Y Zhao, X Liao, W Shi, K Li… - Briefings in functional …, 2019 - academic.oup.com
Omics, such as genomics, transcriptome and proteomics, has been affected by the era of big data. A huge amount of high dimensional and complex structured data has made it no …