[HTML][HTML] Pharmaceutical amorphous solid dispersion: A review of manufacturing strategies
SV Bhujbal, B Mitra, U Jain, Y Gong, A Agrawal… - … Pharmaceutica Sinica B, 2021 - Elsevier
Amorphous solid dispersions (ASDs) are popular for enhancing the solubility and
bioavailability of poorly water-soluble drugs. Various approaches have been employed to …
bioavailability of poorly water-soluble drugs. Various approaches have been employed to …
Recent advances in amorphous solid dispersions: preformulation, formulation strategies, technological advancements and characterization
Amorphous solid dispersions (ASDs) are among the most popular and widely studied
solubility enhancement techniques. Since their inception in the early 1960s, the formulation …
solubility enhancement techniques. Since their inception in the early 1960s, the formulation …
Hydroxypropyl methylcellulose acetate succinate as an exceptional polymer for amorphous solid dispersion formulations: A review from bench to clinic
A Butreddy - European Journal of Pharmaceutics and …, 2022 - Elsevier
Amorphous solid dispersions (ASDs) are a proven system for achieving a supersaturated
state of drug, in which the concentration of drug is greater than its crystalline solubility. The …
state of drug, in which the concentration of drug is greater than its crystalline solubility. The …
[HTML][HTML] Advances in the development of amorphous solid dispersions: The role of polymeric carriers
J Zhang, M Guo, M Luo, T Cai - Asian Journal of Pharmaceutical Sciences, 2023 - Elsevier
Amorphous solid dispersion (ASD) is one of the most effective approaches for delivering
poorly soluble drugs. In ASDs, polymeric materials serve as the carriers in which the drugs …
poorly soluble drugs. In ASDs, polymeric materials serve as the carriers in which the drugs …
Development of cellulose nanofibril/casein-based 3D composite hemostasis scaffold for potential wound-healing application
SS Biranje, J Sun, L Cheng, Y Cheng… - … applied materials & …, 2022 - ACS Publications
Excessive bleeding in traumatic hemorrhage is the primary concern for natural wound
healing and the main reason for trauma deaths. The three-dimensional (3D) bioprinting of …
healing and the main reason for trauma deaths. The three-dimensional (3D) bioprinting of …
Eutectic mixtures as an approach to enhance solubility, dissolution rate and oral bioavailability of poorly water-soluble drugs
Eutectic mixtures have been known for a long time in the pharmaceutical field. However, its
potential as a system to improve the solubility and dissolution of poorly water-soluble drugs …
potential as a system to improve the solubility and dissolution of poorly water-soluble drugs …
Particle size reduction techniques of pharmaceutical compounds for the enhancement of their dissolution rate and bioavailability
In pharmaceutical research and development, various new chemical entities (NCE) are
found to be poorly water-soluble. Therefore, solubility enhancement, a key factor for higher …
found to be poorly water-soluble. Therefore, solubility enhancement, a key factor for higher …
High drug-loading and controlled-release hydroxyphenyl-polyacrylate adhesive for transdermal patch
S Zhang, C Liu, Y Song, J Ruan, P Quan… - Journal of Controlled …, 2023 - Elsevier
Long-acting transdermal drug delivery system (TDDS) requires high drug-loading and drug
controlled-release. To simultaneously improve drug-polymer miscibility and realize drug …
controlled-release. To simultaneously improve drug-polymer miscibility and realize drug …
Direct powder extrusion 3d printing of praziquantel to overcome neglected disease formulation challenges in paediatric populations
For the last 40 years, praziquantel has been the standard treatment for schistosomiasis, a
neglected parasitic disease affecting more than 250 million people worldwide. However …
neglected parasitic disease affecting more than 250 million people worldwide. However …
Amorphous solid dispersions (asds): The influence of material properties, manufacturing processes and analytical technologies in drug product development
R Iyer, V Petrovska Jovanovska, K Berginc, M Jaklič… - Pharmaceutics, 2021 - mdpi.com
Poorly water-soluble drugs pose a significant challenge to developability due to poor oral
absorption leading to poor bioavailability. Several approaches exist that improve the oral …
absorption leading to poor bioavailability. Several approaches exist that improve the oral …