Proteins that self-assemble into polyhedral shell-like structures are useful molecular
containers both in nature and in the laboratory. Here we review efforts to repurpose diverse …

The nucleocapsid phosphoprotein of the severe acute respiratory syndrome coronavirus
(SARS-CoV N protein) packages the viral genome into a helical ribonucleocapsid (RNP) …

Viruses are nanoscale entities containing a nucleic acid genome encased in a protein shell
called a capsid and in some cases are surrounded by a lipid bilayer membrane. This review …

Abstract Hepatitis B Virus (HBV) is a small virus whose genome has only four open reading
frames. We argue that the simplicity of the virion correlates with a complexity of functions for …

Despite remarkable advances over the past several decades, many therapeutic
nanomaterials fail to overcome major in vivo delivery barriers. Controlling immunogenicity …

Self-assembly is a ubiquitous process in synthetic and biological systems, broadly defined
as the spontaneous organization of multiple subunits (macromolecules, particles, etc.) into …

With few exceptions, the shells (capsids) of sphere-like viruses have the symmetry of an
icosahedron and are composed of coat proteins (subunits) assembled in special motifs, the …

Most viruses use a hollow protein shell, the capsid, to enclose the viral genome. Virus
capsids are large, symmetric oligomers made of many copies of one or a few types of protein …

Viruses play a role in a significant portion of human diseases, as well as those of other
animals, plants, and bacteria. This chapter focuses on the use of theoretical and …

Hepatitis B virus (HBV) capsid assembly is a critical step in the propagation of the virus and
is mediated by the core protein. Due to its multiple functions in the viral life cycle, core …