Optimization is a very broad field of research with a wide spectrum of important applications.
Until the 1950s, optimization was understood as a single-objective optimization, ie, as the …

Protein topology diagrams are 2D representations of protein structure that are particularly
useful in understanding and analysing complex protein folds. Generating such diagrams …

Background Systems biology projects and omics technologies have led to a growing
number of biochemical pathway models and reconstructions. However, the majority of these …

Over the last 50 years a wide variety of automatic network layout algorithms have been
developed. Some are fast heuristic techniques suitable for networks with hundreds of …

We explore the effectiveness of visualizing dense directed graphs by replacing individual
edges with edges connected to'modules'-or groups of nodes-such that the new edges imply …

Prior research into network layout has focused on fast heuristic techniques for layout of large
networks, or complex multi-stage pipelines for higher quality layout of small graphs …

This article reviews two decades of research in topics in Information Visualisation emerging
from the Data Visualisation and Immersive Analytics Lab at Monash University Australia …

We propose a new approach to edge bundling. At the first stage we route the edge paths so
as to minimize a weighted sum of the total length of the paths together with their ink. As this …

We present a method for the layout of anatomical structures and blood vessels based on
information from the Foundational Model of Anatomy (FMA). Our approach integrates a …

Background Biologists make frequent use of databases containing large and complex
biological networks. One popular database is the Kyoto Encyclopedia of Genes and …