Discovery of small-molecule antagonists of the H3K9me3 binding to UHRF1 tandem tudor domain

G Senisterra, HY Zhu, X Luo, H Zhang… - … Life Sciences R&D, 2018 - journals.sagepub.com
Ubiquitin-like with PHD and RING finger domains 1 (UHRF1) is a multidomain protein that
plays a critical role in maintaining DNA methylation patterns through concurrent recognition …

In (ONf) 3-catalyzed 7-membered carbon-ring-forming annulation of heteroarylindoles with α, β-unsaturated carbonyl compounds

T Tsuchimoto, T Johshita, K Sambai… - Organic Chemistry …, 2021 - pubs.rsc.org
A seven-membered carbon-ring-forming annulation occurred, upon treatment of
heteroarylindoles with α, β-unsaturated carbonyl compounds in the presence of an indium …

Aromatic Substitution

MR Crampton - … Reaction Mechanisms· 2017: An annual survey …, 2020 - Wiley Online Library
Summary This Chapter Contains Sections titled: Introduction General Nucleophilic
Substitution The S NAr Mechanism Meisenheimer and Related Complexes Benzyne and …

[PDF][PDF] СИНТЕЗ И ПРЕВРАЩЕНИЯ ПРОИЗВОДНЫХ МЕТИЛ 4H-ТИЕНО [3.2-B] ПИРРОЛ-5-КАРБОКСИЛАТА

ЗФ Нуриахметова - ufaras.ru
Актуальность темы. Более 60% известных природных и синтетических лекарственных
средств созданы на основе гетероциклических соединений. Разработка практичных …

Bicyclic 5-6 Systems With One Bridgehead (Ring Junction) Nitrogen Atom: Two Extra Heteroatoms 0: 2

C Lalli - Comprehensive Heterocyclic Chemistry IV, 2022 - univ-rennes.hal.science
Reactivity of substituents attached to ring carbon atoms 9 8 Ring syntheses classified by
number of ring atoms in each component 12 8.1 Pyrrolo [1, 2-b][1, 2, 4] triazine 12 8.2 …