Pharmacological activities and therapeutic potential of Hyperoside in the treatment of Alzheimer's and Parkinson's diseases: A systemic review

J Yuan, X Dong, S Zhou, J Nao - Neuroscience, 2024 - Elsevier
Alzheimer's disease (AD) and Parkinson's disease (PD) are neurodegenerative disorders
that significantly impact well-being. Hyperoside (HYP), a flavonoid found in various plant …

[HTML][HTML] Exploring Potential Mechanisms Accounting for Iron Accumulation in the Central Nervous System of Patients with Alzheimer's Disease

SM LeVine - Cells, 2024 - mdpi.com
Elevated levels of iron occur in both cortical and subcortical regions of the CNS in patients
with Alzheimer's disease. This accumulation is present early in the disease process as well …

The Interplay Between Ferroptosis and Inflammation: Therapeutic Implications for Cerebral Ischemia-Reperfusion

Y He, J Wang, C Ying, KL Xu, J Luo, B Wang… - Frontiers in …, 2024 - frontiersin.org
Stroke ranks as the second most significant contributor to mortality worldwide and is a major
factor in disability. Ischemic strokes account for 71% of all stroke incidences globally. The …

[HTML][HTML] The role of ferroptosis in neurodegenerative diseases

Y Fei, Y Ding - Frontiers in Cellular Neuroscience, 2024 - frontiersin.org
Ferroptosis represents an iron− and lipid peroxidation (LPO)-mediated form of regulated cell
death (RCD). Recent evidence strongly suggests the involvement of ferroptosis in various …

[HTML][HTML] Sex-Biased Associations of Circulating Ferroptosis Inhibitors with Reduced Lipid Peroxidation and Better Neurocognitive Performance in People with HIV

H Kaur, RK Alluri, K Wu, RC Kalayjian, WS Bush… - Antioxidants, 2024 - mdpi.com
Ferroptosis is implicated in viral neuropathogenesis and may underlie HIV-associated
neurocognitive impairment (NCI). Emerging data also suggest differences in brain iron …

[HTML][HTML] Oxidative Stress and Neurodegeneration: Insights and Therapeutic Strategies for Parkinson's Disease

E Bej, P Cesare, AR Volpe, M d'Angelo… - Neurology …, 2024 - mdpi.com
Parkinson's disease (PD) is a progressive neurodegenerative condition marked by the
gradual deterioration of dopaminergic neurons in the substantia nigra. Oxidative stress has …

Neuroinflammation at the crossroads of metabolic and neurodegenerative diseases: Causes, consequences and interventions.

R Pathak, S Sharma, M Bhandari… - Journal of …, 2024 - search.ebscohost.com
Neuroinflammation is increasingly recognized as a pivotal factor not only in
neurodegenerative diseases such as Alzheimer's and Parkinson's, but also in the …

[PDF][PDF] Pazopanib: Effective monotherapy for precise cancer treatment, targeting specific mutations and tumors

R Pathak, V Kaur, S Sharma, M Bhandari, R Mishra… - Cancer, 2024 - researchgate.net
Cancer is a wide range of illnesses characterized by the expansion of abnormal cells with
the ability to invade and damage healthy bodily tissue. Cancer is treated with a variety of …

[HTML][HTML] Strategies to Counteract Oxidative Stress and Inflammation in Chronic-Degenerative Diseases 2.0

C Prata, C Angeloni, T Maraldi - International Journal of Molecular …, 2024 - mdpi.com
Oxidative stress and inflammation are recognized as pivotal contributors and common
features of several chronic degenerative diseases, including cancer, metabolic syndrome …