One of the adverse outcomes of acute inflammatory response is progressing to the chronic
stage or transforming into an aggressive process, which can develop rapidly and result in …

Heart failure (HF) is a highly morbid syndrome that seriously affects the physical and mental
health of patients and generates an enormous socio-economic burden. In addition to cardiac …

Rheumatoid arthritis (RA) is a chronic inflammatory disease that eventually leads to
disability. Inflammatory cell infiltration, severe joint breaking and systemic bone loss are the …

Nephrotoxicity is a major complication that limits the therapeutic application of cisplatin
(CIS). Oxidative stress and inflammation are implicated in CIS-induced acute kidney injury …

Myocardial injury and cardiovascular dysfunction are serious consequences of sepsis and
contribute to high mortality. Currently, the pathogenesis of myocardial injury in sepsis is still …

Ferroptosis contributes to the pathogenesis of atrial fibrillation (AF), although the
mechanisms are still largely uncovered. The current study was designed to explore the …

Background The aggressive phenotype of fibroblast-like synoviocytes (FLSs) is essential in
the synovitis and bone destruction in rheumatoid arthritis (RA). Punicalagin is a natural …

Context Punicalagin has myocardial protection; the mechanism of punicalagin on ventricular
remodeling (VR) after acute myocardial infarction (AMI) remains unclear. Objective These …

Skin ageing is characterized by features such as wrinkles, loss of elasticity, laxity, rough-
textured appearance, melasma and freckles. Several researches have focused for …

Atherosclerotic cardiovascular disease (ACVD) is the leading cause of death worldwide.
Although current therapies, such as statins, have led to a marked reduction in morbidity and …