Calcinosis cutis is the deposition of insoluble calcium in the skin and subcutaneous tissues.
It represents a major clinical problem in patients with SSc affecting at least one quarter of …

Background Skin ulcers (SU) are one of the most frequent manifestations of systemic
sclerosis (SSc). SSc-SU are very painful, often persistent and recurrent; they may lead to …

Microcirculation impairment and related vasculopathy are hallmarks of systemic sclerosis
(SSc). Digital ulceration is second only to Raynaud's phenomenon as a vascular …

Aim Patients with systemic sclerosis (SSc) are at increased risk of cancer, a growing cause
of non–SSc-related death among these patients. We analyzed the increased cancer risk …

Objective To describe demographic, clinical and laboratory features of systemic sclerosis
sine scleroderma (ssSSc) in a large multicentre systemic sclerosis (SSc) cohort. Methods …

Background To determine whether lung involvement is related to microvascular
perturbations, nailfold videocapillaroscopy (NVC) was performed in patients with systemic …

Importance Systemic sclerosis (SSc) sine scleroderma (ssSSc) is a subset of SSc defined by
the absence of skin fibrosis. Little is known about the natural history and skin manifestations …

Introduction The aim of this study was to evaluate the associations between malnutrition and
the clinical features of the disease and depression in patients with systemic sclerosis (SSc) …

Introduction Systemic sclerosis (SSc) is a rare autoimmune disease currently classified into
two subgroups based on skin extension. The aim of this study was to determine in a large …

Introduction Calcinosis cutis is a debilitating complication of systemic sclerosis (SSc). We
previously developed a radiographic scoring system to assess severity of calcinosis …