The treatment of women's health-related conditions, including reproductive tract and
pregnancy disorders, faces distinct challenges and microenvironments, such as the vaginal …

Endometriosis is characterized by the growth of endometrial-like tissue outside the uterus. It
affects many women during their reproductive age, causing years of pelvic pain and …

The female upper genital tract (UGT) hosts important reproductive organs including the
cervix, uterus, fallopian tubes, and ovaries. Several pathologies affect these organ systems …

Suicide gene therapy was suggested as a possible strategy for the treatment of uterine
fibroids (UFs), which are the most common benign tumors inwomen of reproductive age. For …

Gene therapy is a powerful tool for the development of new treatment strategies for various
conditions, by aiming to transport biologically active nucleic acids into diseased cells. To …

Endometriosis and adenomyosis are two similar gynecological diseases that are
characterized by ectopic implantation and the growth of the endometrial tissue. Previous …

Anti-angiogenic RNAi-based therapy can be considered as a possible strategy for the
treatment of endometriosis (EM), which is the most common gynecological disease …

Polyethyleneimine, poly-L-lysine, chitosan and some others cationic polymers have been
thoroughly studied as nucleic acid delivery systems in gene therapy. However, the drug …

Efficient and specific delivery of nucleic acid (NA) therapeutics to tumor cells is extremely
important for cancer gene therapy. Various therapeutic strategies include delivery of DNA …

Background: Angiogenesis is one of the critical physiological processes, by which the new
blood vessels are generated from the pre-existing vessels in the early stage of …