Compounds incorporating guanidine moieties constitute a versatile class of biologically
interesting molecules with a wide array of applications. As such, guanidines have been …

Over the years, researchers in drug discovery have taken advantage of the use of privileged
structures to design innovative hit/lead molecules. The α-ketoamide motif is found in many …

Covering: 2017–2019 Guanidine natural products isolated from microorganisms, marine
invertebrates and terrestrial plants, amphibians and spiders, represented by non-ribosomal …

Ligustrazine is a main active fraction of the traditional medicine known as Ligusticum
chuanxiong hort, which has been used as clinical medication for cerebral thrombosis …

The rapid growth of antimicrobial resistance against several frontline antibiotics has
encouraged scientists worldwide to develop new alternatives with unique mechanisms of …

The clinical effectiveness of the important β-lactam class of antibiotics is under threat by the
emergence of resistance, mostly due to the production of acquired serine-(SBL) and metallo …

Uranium seawater extraction is strategically important to the sustainable development of
nuclear energy. Nevertheless, a challenge remains in uranium enrichment to overcome the …

This review identifies the ways in which tethered bilayer lipid membranes (tBLMs) can be
used for the identification of the actions of antimicrobials against lipid bilayers. Much of the …

The ongoing battle against viral pandemics continues, with the possibility of future
outbreaks. The search for effective antiviral compounds that can combat a diverse range of …

The major challenge in bacterial infection in clinical settings is the development of
antimicrobial materials in the treatment of drug-resistant bacteria. Herein, we report a new …