SUMOylation in viral replication and antiviral defense
SUMOylation is a ubiquitination‐like post‐translational modification that plays an essential
role in the regulation of protein function. Recent studies have shown that proteins from both …
role in the regulation of protein function. Recent studies have shown that proteins from both …
Crosstalk between nucleocytoplasmic trafficking and the innate immune response to viral infection
The nuclear pore complex is the sole gateway connecting the nucleoplasm and cytoplasm.
In humans, the nuclear pore complex is one of the largest multiprotein assemblies in the cell …
In humans, the nuclear pore complex is one of the largest multiprotein assemblies in the cell …
Roles of nucleoporin RanBP2/Nup358 in acute necrotizing encephalopathy type 1 (ANE1) and viral infection
Ran Binding Protein 2 (RanBP2 or Nucleoporin358) is one of the main components of the
cytoplasmic filaments of the nuclear pore complex. Mutations in the RANBP2 gene are …
cytoplasmic filaments of the nuclear pore complex. Mutations in the RANBP2 gene are …
RANBP2 evolution and human disease
S Desgraupes, L Etienne, NJ Arhel - FEBS letters, 2023 - Wiley Online Library
Ran‐binding protein 2 (RANBP2)/Nup358 is a nucleoporin and a key component of the
nuclear pore complex. Through its multiple functions (eg, SUMOylation, regulation of …
nuclear pore complex. Through its multiple functions (eg, SUMOylation, regulation of …
How non-enveloped viruses hijack host machineries to cause infection
CC Spriggs, MC Harwood, B Tsai - Advances in virus research, 2019 - Elsevier
Viruses must navigate the complex endomembranous network of the host cell to cause
infection. In the case of a non-enveloped virus that lacks a surrounding lipid bilayer …
infection. In the case of a non-enveloped virus that lacks a surrounding lipid bilayer …
Multifunctionality of F-rich nucleoporins
Nucleoporins (Nups) represent a range of proteins most known for composing the
macromolecular assembly of the nuclear pore complex (NPC). Among them, the family of …
macromolecular assembly of the nuclear pore complex (NPC). Among them, the family of …
Acute necrotizing encephalopathy-linked mutations in Nup358 impair interaction of Nup358 with TNRC6/GW182 and miRNA function
P Deshmukh, A Singh, D Khuperkar… - … and Biophysical Research …, 2021 - Elsevier
MicroRNA (miRNA)-mediated translational suppression of mRNAs is involved in the
regulation of multiple cellular processes. A recent study showed that Nup358, a protein …
regulation of multiple cellular processes. A recent study showed that Nup358, a protein …
Targeting Nup358/RanBP2 by a viral protein disrupts stress granule formation
J Sadasivan, M Vlok, X Wang, A Nayak… - PLoS …, 2022 - journals.plos.org
Viruses have evolved mechanisms to modulate cellular pathways to facilitate infection. One
such pathway is the formation of stress granules (SG), which are ribonucleoprotein …
such pathway is the formation of stress granules (SG), which are ribonucleoprotein …
Targeting nuclear proteins for control of viral replication
W Meng, XJ Wang, HCR Wang - Critical reviews in microbiology, 2019 - Taylor & Francis
Viruses are obligate intracellular parasites that exploit host cell machineries for replication.
In this review, we focus on the current understanding of host cell nuclear proteins whose …
In this review, we focus on the current understanding of host cell nuclear proteins whose …
Sequestration of late antigens within viral factories impairs MVA vector-induced protective memory CTL responses
S Tao, R Tao, DH Busch, M Widera, H Schaal… - Frontiers in …, 2019 - frontiersin.org
Cytotoxic CD8+ T cell (CTL) responses play an essential role in antiviral immunity. Here, we
focused on the activation of CTL which recognize epitopes derived from viral or recombinant …
focused on the activation of CTL which recognize epitopes derived from viral or recombinant …