The PR/SET domain family (PRDM) comprise a family of genes whose protein products
share a conserved N-terminal PR [PRDI-BF1 (positive regulatory domain I-binding factor 1) …

Histone acetylation, one of the first and best studied histone post-translational modifications
(PTMs), as well as the factors involved in its deposition (writers), binding (readers) and …

PRDM9 (PR domain-containing protein 9) is a meiosis-specific protein that trimethylates
H3K4 and controls the activation of recombination hot spots. It is an essential enzyme in the …

Objectives To investigate the treatment effects of endoscopic submucosal dissection (ESD)
versus endoscopic mucosal resection (EMR) for early gastric cancer (EGC). Design Meta …

Cancer cells have many abnormal characteristics enabling tumors to grow, spread, and
avoid immunologic and therapeutic destruction. Central to this is the innate ability of …

Background Chromatin loops form a basic unit of interphase nuclear organization, with
chromatin loop anchor points providing contacts between regulatory regions and promoters …

Simple Summary Epigenetic modifications can regulate gene expression by altering
chromatin structure. Since the beginning of comprehensive research into changes in gene …

PRDF1 and RIZ1 homology domain containing (PRDMs) are a subfamily of Krüppel‐like
zinc finger proteins controlling key processes in metazoan development and in cancer …

Abnormal gene expression in cancer represents an under-explored source of cancer
markers and therapeutic targets. In order to identify gene expression signatures associated …

Mobilization of retrotransposons to new genomic locations is a significant driver of
mammalian genome evolution, but these mutagenic events can also cause genetic …