Arginine methylation is a ubiquitous and relatively stable post-translational modification
(PTM) that occurs in three types: monomethylarginine (MMA), asymmetric dimethylarginine …

Histone methylation reader domains are protein modules that recognize specific histone
methylation marks, such as methylated or unmethylated lysine or arginine residues on …

SMNDC1 is a Tudor domain protein that recognizes di-methylated arginines and controls
gene expression as an essential splicing factor. Here, we study the specific contributions of …

Amyotrophic lateral sclerosis (ALS) is linked to the reduction of certain nucleoporins in
neurons. Increased nuclear localization of charged multivesicular body protein 7 (CHMP7) …

Biomolecular condensates (BMCs) can facilitate or inhibit diverse cellular functions. BMC
formation is driven by noncovalent protein–protein, protein–RNA, and RNA–RNA …

Tudor domain-containing protein 3 (TDRD3) is involved in regulating transcription and
translation, promoting breast cancer progression, and modulating neurodevelopment and …

Cosolvent molecular dynamics (MD) simulations have proven to be powerful in silico tools to
predict hotspots for binding regions on protein surfaces. In the current study, the method was …

Tudor domains are histone readers that can recognize various methylation marks on lysine
and arginine. This recognition event plays a key role in the recruitment of other epigenetic …

Staphylococcal nuclease Tudor domain containing 1 (SND1) protein is an oncogene that
'reads' methylarginine marks through its Tudor domain. Specifically, it recognizes …

Ketenimines represent an important class of reactive species, useful synthetic intermediates,
and synthons. However, in general, ketenimines preferentially undergoes nucleophilic …