The emerging links between our gut microbiome and the central nervous system are
regarded as a paradigm shift in neuroscience with possible implications for not only …

The gut barrier plays a crucial role by spatially compartmentalizing bacteria to the lumen
through the production of secreted mucus and is fortified by the production of secretory IgA …

Data are accumulating that emphasize the important role of the intestinal barrier and
intestinal permeability for health and disease. However, these terms are poorly defined, their …

Metabolites present in human blood document individual physiological states influenced by
genetic, epigenetic, and lifestyle factors. Using high-resolution liquid chromatography-mass …

Immune-checkpoint inhibitors (ICI) now represent the standard of care for several cancer
types. In pre-clinical models, absence of an intact gut microbiome negatively impacted ICI …

BACKGROUND & AIMS: Teduglutide, a glucagon-like peptide 2 analogue, might restore
intestinal structural and functional integrity by promoting growth of the mucosa and reducing …

Systemic immune activation is increased in HIV-infected individuals, even in the setting of
virus suppression with antiretroviral therapy. Although numerous factors may contribute …

Background and aims Teduglutide, a GLP-2 analogue, may restore intestinal structural and
functional integrity by promoting repair and growth of the mucosa and reducing gastric …

Home parenteral nutrition (HPN) was introduced as a treatment modality in the early 1970s
primarily for the treatment of chronic intestinal failure in patients with benign disease. The …

Citrulline (Cit, C 6 H 13 N 3 O 3), which is a ubiquitous amino acid in mammals, is strongly
related to arginine. Citrulline metabolism in mammals is divided into two fields: free citrulline …