The benefits of exercise on the heart are well recognized, and clinical studies have
demonstrated that exercise is an intervention that can improve cardiac function in heart …

Despite the significant decline in mortality, cardiovascular diseases are still the leading
cause of death worldwide. Among them, myocardial infarction (MI) seems to be the most …

Low-grade systemic inflammation associated to obesity leads to cardiovascular
complications, caused partly by infiltration of adipose and vascular tissue by effector T cells …

Over the past 30 years the mitochondrial permeability transition–the permeabilization of the
inner mitochondrial membrane due to the opening of a wide pore–has progressed from …

Regular physical activity or exercise training can lead to heart enlargement known as
cardiac hypertrophy. Cardiac hypertrophy is broadly defined as an increase in heart mass. In …

Abstract Background Remote ischemic perconditioning (RIPerC) has a promising
therapeutic insight to improve the prognosis of acute myocardial infarction. Chronic …

Excessive Ultra-violet (UV) radiation causes oxidative damages and apoptosis in retinal
pigment epithelium (RPE) cells. Here we tested the potential activity of SC79, a novel small …

Ischemic preconditioning is a process which serves to mitigate reperfusion injury.
Preconditioning of the heart can be achieved through natural, pharmacological, and …

Dexamethasone (Dex) causes osteoblast cell injuries. In the present research, we tested the
potential effect of SC79, a novel and specific Akt activator, against Dex in osteoblasts. In …

Alzheimer's disease (AD) is a form of dementia marked by the accumulation of neuritic
plaques and neurofibrillary tangles through the action of GSK-3β with both significant …