Metastasis or the progression of malignancy poses a major challenge in cancer therapy and
is the principal reason for increased mortality. The epithelial-mesenchymal transition (EMT) …

Integrins are transmembrane receptors that possess distinct ligand-binding specificities in
the extracellular domain and signaling properties in the cytoplasmic domain. While most …

As the worldwide prevalence of chronic liver diseases is high and continuing to increase,
there is an urgent need for treatment to prevent cirrhosis‐related morbidity and mortality …

CAR (CARSKNKDC) is a wound-homing peptide that recognises angiogenic neovessels.
Here we discover that systemically administered CAR peptide has inherent ability to …

Heterogeneity within the glycocalyx influences cell adhesion mechanics and signaling.
However, the role of specific glycosylation subtypes in influencing cell mechanics via …

Fibrosis is a pathological process characterized by accumulation of fibrous connective tissue
in organs, leading to organ malfunction and failure. At the cellular level, tissue injury or …

There is currently an increased interest in understanding the role of the tumor
microenvironment (TME) in tumor growth and progression. In this context the role of integrins …

Introduction Breast cancer (BC) is the leading cause of death among women, primarily due
to its potential for metastasis. As BC progresses, the extracellular matrix (ECM) produces …

Human‐induced pluripotent stem cells (hiPSCs) have great therapeutic potential. The cell
source differentiated from hiPSCs requires xeno‐free and robust methods for lineage …

While adhering to extracellular matrix (ECM) proteins, such as laminin-111, cells temporarily
produce hydrogen peroxide at adhesion sites. To study the redox regulation of α7β1 integrin …