A survey on adverse drug reaction studies: data, tasks and machine learning methods

DA Nguyen, CH Nguyen… - Briefings in …, 2021 - academic.oup.com
Motivation Adverse drug reaction (ADR) or drug side effect studies play a crucial role in drug
discovery. Recently, with the rapid increase of both clinical and non-clinical data, machine …

CeDR Atlas: a knowledgebase of cellular drug response

YY Wang, H Kang, T Xu, L Hao, Y Bao… - Nucleic acids …, 2022 - academic.oup.com
Drug response to many diseases varies dramatically due to the complex genomics and
functional features and contexts. Cellular diversity of human tissues, especially tumors, is …

Machine learning workflow to enhance predictions of Adverse Drug Reactions (ADRs) through drug-gene interactions: application to drugs for cutaneous diseases

K Raja, M Patrick, JT Elder, LC Tsoi - Scientific reports, 2017 - nature.com
Adverse drug reactions (ADRs) pose critical public health issues, affecting over 6% of
hospitalized patients. While knowledge of potential drug-drug interactions (DDI) is …

Predicting drug side effects using data analytics and the integration of multiple data sources

WP Lee, JY Huang, HH Chang, KT Lee, CT Lai - IEEE Access, 2017 - ieeexplore.ieee.org
The development of automated approaches employing computational methods using data
from publicly available drugs datasets for the prediction of drug side effects has been …

Predicting adverse drug reactions of two‐drug combinations using structural and transcriptomic drug representations to train an artificial neural network

S Shankar, I Bhandari, DT Okou… - Chemical Biology & …, 2021 - Wiley Online Library
Adverse drug reactions (ADRs) are pharmacological events triggered by drug interactions
with various sources of origin including drug–drug interactions. While there are many …

[Retracted] A Data‐Driven Medical Decision Framework for Associating Adverse Drug Events with Drug‐Drug Interaction Mechanisms

A Noor - Journal of Healthcare Engineering, 2022 - Wiley Online Library
Adverse drug events (ADEs) occur when multiple drugs interact within an individual, thus
causing effects that were not initially predicted. Such toxic interactions lead to morbidity and …

Discovering synergistic drug combination from a computational perspective

P Ding, J Luo, C Liang, Q Xiao… - Current Topics in …, 2018 - ingentaconnect.com
Synergistic drug combinations play an important role in the treatment of complex diseases.
The identification of effective drug combination is vital to further reduce the side effects and …

Literature based discovery of alternative TCM medicine for adverse reactions to depression drugs

Q Xie, KM Yang, GE Heo, M Song - BMC bioinformatics, 2020 - Springer
Abstract Background In recent years, Traditional Chinese Medicine (TCM) and alternative
medicine have been widely used along with western drugs as a complementary form of …

The fuzzy system as a promising tool for drugs selection in medical practice

M Fedorova, D Perdukova, Z Pirnik, V Fedak… - IEEE …, 2018 - ieeexplore.ieee.org
The aim of this paper was to demonstrate the potential of the fuzzy system approach to the
analysis of healthcare databases for clinicians in their routine daily practice. The healthcare …

Recent advances in computational approaches for designing potential anti-alzheimer's agents

S Gomez-Ganau, JV de Julián-Ortiz… - … Modeling of Drugs …, 2018 - Springer
Alzheimer's disease (AD) is the leading cause of dementia in old people worldwide and one
of the leading causes of death in developed countries. The current poor understanding of …