New progress in the pharmacology of protocatechuic acid: A compound ingested in daily foods and herbs frequently and heavily

J Song, Y He, C Luo, B Feng, F Ran, H Xu, Z Ci… - Pharmacological …, 2020 - Elsevier
Protocatechuic acid is a natural phenolic acid, which widely exists in our daily diet and
herbs. It is also one of the main metabolites of complex polyphenols, such as anthocyanins …

Antioxidant effects of protocatechuic acid and protocatechuic aldehyde: old wine in a new bottle

S Zhang, Z Gai, T Gui, J Chen… - Evidence‐Based …, 2021 - Wiley Online Library
Phenolic compounds are naturally present as secondary metabolites in plant‐based
sources such as fruits, vegetables, and spices. They have received considerable attention …

Protocatechuic acid mitigates cadmium-induced neurotoxicity in rats: Role of oxidative stress, inflammation and apoptosis

EM Al Olayan, AS Aloufi, OD AlAmri, H Ola… - Science of the total …, 2020 - Elsevier
Environmental and occupational exposure to heavy metals, including cadmium (Cd), is
associated with extremely adverse impacts to living systems. Antioxidant agents are …

Beneficial effects of dietary polyphenols on high-fat diet-induced obesity linking with modulation of gut microbiota

J Liu, Z He, N Ma, ZY Chen - Journal of Agricultural and Food …, 2019 - ACS Publications
Obesity is caused by an imbalance of energy intake and expenditure. It is characterized by a
higher accumulation of body fat with a chronic low-grade inflammation. Many reports have …

Anthocyanins: traditional uses, structural and functional variations, approaches to increase yields and products' quality, hepatoprotection, liver longevity, and …

HA Mohammed, RA Khan - International Journal of Molecular Sciences, 2022 - mdpi.com
Anthocyanins are water-soluble, colored compounds of the flavonoid class, abundantly
found in the fruits, leaves, roots, and other parts of the plants. The fruit berries are prime …

Premature birth, low birth weight, small for gestational age and chronic non-communicable diseases in adult life: A systematic review with meta-analysis

ELSS de Mendonça, M de Lima Macêna… - Early human …, 2020 - Elsevier
Background Individuals who were born prematurely (PT), with low birth weight (LBW), or
small for gestational age (SGA) appear to present a set of permanent changes that make …

Anthocyanins as promising molecules affecting energy homeostasis, inflammation, and gut microbiota in type 2 diabetes with special reference to impact of acylation

K Chen, MK Kortesniemi, KM Linderborg… - Journal of Agricultural …, 2022 - ACS Publications
Anthocyanins, the red-orange to blue-violet colorants present in fruits, vegetables, and
tubers, have antidiabetic properties expressed via modulating energy metabolism …

Associations of the cardiometabolic index with the risk of cardiovascular disease in patients with hypertension and obstructive sleep apnea: results of a longitudinal …

X Cai, J Hu, W Wen, J Wang, M Wang… - Oxidative Medicine …, 2022 - Wiley Online Library
Purpose. We aimed to explore the relationship between the cardiometabolic index (CMI)
and cardiovascular disease (CVD) and its subtypes (coronary artery disease and stroke) in …

The role of JNk signaling pathway in obesity-driven insulin resistance

J Feng, S Lu, B Ou, Q Liu, J Dai, C Ji… - … syndrome and obesity, 2020 - Taylor & Francis
Obesity is not only closely related to insulin resistance but is one of the main factors leading
to the formation of Type 2 Diabetes (T2D) too. The c-Jun N-terminal kinase (JNK) family is a …

Dietary flavonoids and insulin signaling in diabetes and obesity

MÁ Martín, S Ramos - Cells, 2021 - mdpi.com
Type 2 diabetes (T2D) and obesity are relevant worldwide chronic diseases. A common
complication in both pathologies is the dysregulation of the insulin-signaling pathway that is …