Background Melatonin is an indole hormone secreted primarily by the pineal gland that
showing anti-oxidant, anti-inflammatory and anti-apoptotic capacity. It can play an important …

Acute optic neuritis is the most common optic neuropathy affecting young adults. Exciting
developments have occurred over the past decade in understanding of optic neuritis …

Seasonal changes in disease activity have been observed in multiple sclerosis, an
autoimmune disorder that affects the CNS. These epidemiological observations suggest that …

Due to the heterogeneous nature of the disease, it is a challenge to capture disease activity
of multiple sclerosis (MS) in a reliable and valid way. Therefore, it can be difficult to assess …

Background We aimed to investigate the effects of ambient respiratory viral infections in the
general population on rheumatoid arthritis (RA) development. Methods Data of weekly …

Autoimmune diseases (ADs) are a heterogeneous groups of diseases that occur as a results
of loss of tolerance to self antigens. While the etiopathogeneis remain obscure, different …

Relapses (episodic exacerbations of neurological signs or symptoms) are a defining feature
of relapsing-remitting multiple sclerosis (MS), the most prevalent MS phenotype. While their …

Over the past several decades, significant advances have been made in identifying factors
that contribute to the pathogenesis of multiple sclerosis (MS) and have culminated in the …

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Multiple sclerosis (MS) is a chronic disease of the central nervous system with an
unidentified etiology. We systematically reviewed the literature on the possible risk factors …