RNA regulons in Hox 5′ UTRs confer ribosome specificity to gene regulation

S Xue, S Tian, K Fujii, W Kladwang, R Das, M Barna - Nature, 2015 - nature.com
Emerging evidence suggests that the ribosome has a regulatory function in directing how
the genome is translated in time and space. However, how this regulation is encoded in the …

Programmable antivirals targeting critical conserved viral RNA secondary structures from influenza A virus and SARS-CoV-2

RJ Hagey, M Elazar, EA Pham, S Tian, L Ben-Avi… - Nature medicine, 2022 - nature.com
Influenza A virus's (IAV's) frequent genetic changes challenge vaccine strategies and
engender resistance to current drugs. We sought to identify conserved and essential RNA …

HiTRACE: high-throughput robust analysis for capillary electrophoresis

S Yoon, J Kim, J Hum, H Kim, S Park… - …, 2011 - academic.oup.com
Motivation: Capillary electrophoresis (CE) of nucleic acids is a workhorse technology
underlying high-throughput genome analysis and large-scale chemical mapping for nucleic …

Deepcci: End-to-end deep learning for chemical-chemical interaction prediction

S Kwon, S Yoon - Proceedings of the 8th ACM international conference …, 2017 - dl.acm.org
Chemical-chemical interaction (CCI) plays a key role in predicting candidate drugs, toxicity,
therapeutic effects, and biological functions. In various types of chemical analyses …

High-throughput mutate-map-rescue evaluates SHAPE-directed RNA structure and uncovers excited states

S Tian, P Cordero, W Kladwang, R Das - Rna, 2014 - rnajournal.cshlp.org
The three-dimensional conformations of noncoding RNAs underpin their biochemical
functions but have largely eluded experimental characterization. Here, we report that …

FingerNet: Deep learning-based robust finger joint detection from radiographs

S Lee, M Choi, H Choi, MS Park… - 2015 IEEE Biomedical …, 2015 - ieeexplore.ieee.org
Radiographic image assessment is the most common method used to measure physical
maturity and diagnose growth disorders, hereditary diseases and rheumatoid arthritis, with …

HiTRACE-Web: an online tool for robust analysis of high-throughput capillary electrophoresis

H Kim, P Cordero, R Das, S Yoon - Nucleic acids research, 2013 - academic.oup.com
To facilitate the analysis of large-scale high-throughput capillary electrophoresis data, we
previously proposed a suite of efficient analysis software named HiTRACE (High …

DNA privacy: analyzing malicious DNA sequences using deep neural networks

H Bae, S Min, HS Choi, S Yoon - IEEE/ACM Transactions on …, 2020 - ieeexplore.ieee.org
Recent advances in next-generation sequencing technologies have led to the successful
insertion of video information into DNA using synthesized oligonucleotides. Several attempts …

[HTML][HTML] Determining RNA three-dimensional structures using low-resolution data

M Parisien, F Major - Journal of structural biology, 2012 - Elsevier
Knowing the 3-D structure of an RNA is fundamental to understand its biological function.
Nowadays X-ray crystallography and NMR spectroscopy are systematically applied to newly …

hc-OTU: A fast and accurate method for clustering operational taxonomic units based on homopolymer compaction

S Park, H Choi, B Lee, J Chun… - … /ACM transactions on …, 2016 - ieeexplore.ieee.org
To assess the genetic diversity of an environmental sample in metagenomics studies, the
amplicon sequences of 16s rRNA genes need to be clustered into operational taxonomic …