When cancer metastasizes to bone, considerable pain and deregulated bone remodelling
occurs, greatly diminishing the possibility of cure. Metastasizing tumour cells mobilize and …

Metastasis is a multistep process that requires acquisition of malignant cell phenotypes
which allow tumor cells to escape from the primary tumor site. Each of the steps during …

Background—Upregulated by atheroprotective flow, the transcription factor Krüppel-like
factor 2 (KLF2) is crucial for maintaining endothelial function. MicroRNAs (miRNAs) are …

Bone marrow–derived endothelial progenitor cells (EPC) contribute to the angiogenesis-
dependent growth of tumors in mice and humans. EPCs regulate the angiogenic switch via …

The enhancement of re-endothelialisation is a critical therapeutic option for repairing injured
blood vessels. Endothelial progenitor cells (EPCs) are the major source of cells that …

Background: Exposure to ambient fine particulate matter air pollution (PM2. 5;< 2.5 µm in
aerodynamic diameter) induces endothelial dysfunction and increases the risk for …

Endothelial progenitor cells (EPCs) have recently been shown to promote the angiogenic
switch in solid neoplasms, thereby promoting tumour growth and metastatisation. The …

Objective To examine the possibility that CXCL16 recruits endothelial cells (ECs) to
developing neovasculature in rheumatoid arthritis (RA) synovium. Methods We utilized the …

Objective—Acrolein is a toxic chemical present in tobacco, wood, and coal smoke, as well
as automobile exhaust. Because exposure to these pollutants is associated with an increase …

Exposure to fine particular matter (PM2. 5) increases the risk of developing cardiovascular
disease and Type 2 diabetes. Because blood vessels are sensitive targets of air pollutant …