Liver disease accounts for two million deaths annually and is responsible for 4% of all
deaths (1 out of every 25 deaths worldwide); approximately two-thirds of all liver-related …

In patients with cirrhosis and chronic liver disease, acute-on-chronic liver failure is emerging
as a major cause of mortality. These guidelines indicate the preferred approach to the …

Methotrexate (MTX) is one of the most effective and widely used drugs in the management of
autoimmune and dermatological diseases. Rheumatoid arthritis and psoriasis patients who …

Globally, nearly half of deaths from cirrhosis and chronic liver diseases (CLD) and three-
quarters of deaths from hepatocellular carcinoma (HCC) occur in the Asia-Pacific region …

Idiosyncratic drug-induced liver injury mimics acute and chronic liver disease. It is under
recognized and underrecognised because of the lack of pathognomonic diagnostic …

The epidemiology and aetiology of drug‐induced liver injury (DILI) vary across different
countries and populations. Overall, DILI is rare in the general population but has become …

The transition from compensated to decompensated cirrhosis results from a complex
interplay of predisposing and precipitating factors and represents an inflection point in the …

慢加急性肝衰竭(ACLF) 是一种在慢性肝病基础上发生肝功能急性失代偿的临床综合征,
目前全球尚无统一定义标准. 其显著特征是肝病进展迅速, 常伴发多器官功能衰竭 …

Background Etiology of and outcomes following idiosyncratic drug-induced liver injury (DILI)
vary geographically. We conducted a prospective study of DILI in India, from 2013 to 2018 …

With growing antipathy toward conventional prescription drugs due to the fear of adverse
events, the general and patient populations have been increasingly using complementary …