An epigenetic role of mitochondria in cancer

Y Liu, C Chen, X Wang, Y Sun, J Zhang, J Chen, Y Shi - Cells, 2022 - mdpi.com
Mitochondria are not only the main energy supplier but are also the cell metabolic center
regulating multiple key metaborates that play pivotal roles in epigenetics regulation. These …

Unravelling the potential of mitochondria-targeted liposomes for enhanced cancer treatment

MS Khan, BHJ Gowda, WH Almalki, T Singh… - Drug Discovery …, 2023 - Elsevier
Highlights•Mitochondria are involved in various physiochemical and biochemical
processes.•Owing to their crucial role in cellular metabolism, mitochondria are favored …

Mitochondrial-targeted nanoparticles: Delivery and therapeutic agents in cancer

C Ganji, V Muppala, M Khan, GP Nagaraju… - Drug discovery today, 2023 - Elsevier
Highlights•Dysregulation of mitochondrial metabolism is a hallmark of cancer development.•
Nanoparticles (NPs) enable the efficient and targeted delivery of mitochondrial agents.•NPs …

Nanocarriers: a reliable tool for the delivery of anticancer drugs

H Sabit, M Abdel-Hakeem, T Shoala, S Abdel-Ghany… - Pharmaceutics, 2022 - mdpi.com
Nanomedicines have gained popularity due to their potential therapeutic applications,
especially cancer treatment. Targeted nanoparticles can deliver drugs directly to cancer …

Recent Advances in Carbon Dots for In Vitro/Vivo Fluorescent Bioimaging: A Mini-Review

C He, X Lin, Y Mei, Y Luo, M Yang, Y Kuang… - Frontiers in …, 2022 - frontiersin.org
As a new type of “zero-dimensional” fluorescent carbon nanomaterials, carbon dots (CDs)
have some unique optical and chemical properties, they are being explored for a variety of …

Identification of SSBP1 as a ferroptosis-related biomarker of glioblastoma based on a novel mitochondria-related gene risk model and in vitro experiments

J Su, Y Li, Q Liu, G Peng, C Qin, Y Li - Journal of Translational Medicine, 2022 - Springer
Background Glioblastoma (GBM) is the most common primary malignant brain tumor that
leads to lethality. Several studies have demonstrated that mitochondria play an important …

Synthesis, biological activity, and molecular modelling studies of naphthoquinone derivatives as promising anticancer candidates targeting COX-2

P Kavaliauskas, FS Opazo, W Acevedo, R Petraitiene… - Pharmaceuticals, 2022 - mdpi.com
Non-small cell lung cancer (NSCLC) remains a leading cause of cancer-associated
mortalities worldwide. Therefore, it is crucial to develop a novel therapeutic option targeting …

Smart design of mitochondria-targeted and ROS-responsive CPI-613 delivery nanoplatform for bioenergetic pancreatic cancer therapy

YM Zhang, M Xia, R Ao, LX Gao, Y Tang, JH Huang… - Nanomaterials, 2021 - mdpi.com
Mitochondria, as the powerhouse of most cells, are not only responsible for the generation of
adenosine triphosphate (ATP) but also play a decisive role in the regulation of apoptotic cell …

Roles of mitochondria in oral squamous cell carcinoma therapy: Friend or foe?

J Bai, L Wu, X Wang, Y Wang, Z Shang, E Jiang… - Cancers, 2022 - mdpi.com
Simple Summary Although many therapies have been applied in oral squamous cell
carcinoma, these therapies are still unsatisfactory. Recently, the mitochondrial role in oral …

[HTML][HTML] Carboxymethylcellulose biofunctionalized ternary quantum dots for subcellular-targeted brain cancer nanotheranostics

AAP Mansur, MRB Paiva, OAL Cotta, LM Silva… - International journal of …, 2022 - Elsevier
Among the most lethal forms of cancer, malignant brain tumors persist as one of the greatest
challenges faced by oncologists, where nanotechnology-driven theranostics can play a …