Candida albicans is a major fungal pathogen of humans. It exists as a commensal in the oral
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …

The epidemiology of invasive fungal infections is changing, with new populations at risk and
the emergence of resistance caused by the selective pressure from increased usage of …

β-Glucans are a heterogeneous group of glucose polymers with a common structure
comprising a main chain of β-(1, 3) and/or β-(1, 4)-glucopyranosyl units, along with side …

The cell wall of Saccharomyces cerevisiae is an elastic structure that provides osmotic and
physical protection and determines the shape of the cell. The inner layer of the wall is largely …

Virulence of Candida is linked with its ability to form biofilms. Once established, biofilm
infections are nearly impossible to eradicate. Biofilm cells live immersed in a self-produced …

Fungal insect pathogens have evolved diverse mechanisms to evade host immune
recognition and defense responses. However, identification of fungal factors involved in host …

In this review, we discuss new insights in cell wall architecture and cell wall construction in
the ascomycetous yeast Saccharomyces cerevisiae. Transcriptional profiling studies …

The Candida albicans cell wall maintains the structural integrity of the organism in addtion to
providing a physical contact interface with the environment. The major components of the …

Candida albicans is part of the normal human flora, and it grows on mucosal surfaces in
healthy individuals. In susceptible hosts, this organism can cause both mucosal and …

The ALS gene family of Candida albicans encodes large cell-surface glycoproteins that are
implicated in the process of adhesion to host surfaces. ALS genes are also found in other …