Recent progress in the development of fluorescent probes for imaging pathological oxidative stress

Y Geng, Z Wang, J Zhou, M Zhu, J Liu… - Chemical Society …, 2023 - pubs.rsc.org
Oxidative stress is closely related to the physiopathology of numerous diseases. Reactive
oxygen species (ROS), reactive nitrogen species (RNS), and reactive sulfur species (RSS) …

Small-molecule fluorescence-based probes for interrogating major organ diseases

HH Han, H Tian, Y Zang, AC Sedgwick, J Li… - Chemical Society …, 2021 - pubs.rsc.org
Chemical tools that allow the real-time monitoring of organ function and the visualisation of
organ-related processes at the cellular level are of great importance in biological research …

Fluorescent small organic probes for biosensing

X Tian, LC Murfin, L Wu, SE Lewis, TD James - Chemical science, 2021 - pubs.rsc.org
Small-molecule based fluorescent probes are increasingly important for the detection and
imaging of biological signaling molecules due to their simplicity, high selectivity and …

Recent advances in small-molecule fluorescent probes for studying ferroptosis

YL Qi, HR Wang, LL Chen, YT Duan… - Chemical Society …, 2022 - pubs.rsc.org
Ferroptosis is an iron-dependent, non-apoptotic form of programmed cell death driven by
excessive lipid peroxidation (LPO). Mounting evidence suggests that the unique modality of …

Green regenerative hydrogel wound dressing functionalized by natural drug‐food homologous small molecule self‐assembled nanospheres

X Sun, P Jia, H Zhang, M Dong, J Wang… - Advanced Functional …, 2022 - Wiley Online Library
The goal of regenerative wound healing dressings is to restore tissue function back to
normal physiological activity and accelerate skin tissue regeneration at wound sites. The …

Two-photon small-molecule fluorescence-based agents for sensing, imaging, and therapy within biological systems

L Wu, J Liu, P Li, B Tang, TD James - Chemical Society Reviews, 2021 - pubs.rsc.org
In this tutorial review, we will explore recent advances for the design, construction and
application of two-photon excited fluorescence (TPEF)-based small-molecule probes. The …

Ferroptosis Accompanied by OH Generation and Cytoplasmic Viscosity Increase Revealed via Dual-Functional Fluorescence Probe

H Li, W Shi, X Li, Y Hu, Y Fang… - Journal of the American …, 2019 - ACS Publications
Ferroptosis, a new form of regulated cell death, results from the iron-dependent
accumulation of lipid peroxides that are associated with reactive oxygen species. However …

Generation of hydroxyl radical-activatable ratiometric near-infrared bimodal probes for early monitoring of tumor response to therapy

L Wu, Y Ishigaki, W Zeng, T Harimoto, B Yin… - Nature …, 2021 - nature.com
Tumor response to radiotherapy or ferroptosis is closely related to hydroxyl radical (• OH)
production. Noninvasive imaging of• OH fluctuation in tumors can allow early monitoring of …

Responsive fluorescent probes for cellular microenvironment and redox small biomolecules

L Zhang, L Zhang, X Zhang, Y Zhao, S Fang… - TrAC Trends in …, 2023 - Elsevier
The living system is critically depended on the inner microenvironment and redox small
biomolecules to maintain the normal physiological processes. Consequently, tracing and …

Fluorescent imaging of reactive oxygen and nitrogen species associated with pathophysiological processes

JT Hou, KK Yu, K Sunwoo, WY Kim, S Koo, J Wang… - Chem, 2020 - cell.com
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) play their essential
roles in regulating biological events. Their aberrant behaviors are mostly associated with …