N-Acylhydrazones as drugs

S Thota, DA Rodrigues, PSM Pinheiro, LM Lima… - Bioorganic & medicinal …, 2018 - Elsevier
Over the last two decades, N-acylhydrazone (NAH) has been proven to be a very versatile
and promising motif in drug design and medicinal chemistry. Herein, we discuss the current …

Anticancer agents incorporating the N‐acylhydrazone scaffold: Progress from 2017 to present

AE Kassab - Archiv der Pharmazie, 2023 - Wiley Online Library
The N‐acylhydrazone motif has been shown to be particularly adaptable and promising in
the area of medicinal chemistry and drug development, due to its significant biological and …

[HTML][HTML] Integration of genotypic data into clinical trial design and reporting in hereditary hemorrhagic telangiectasia could help personalize treatment

A Modarresi, CL Shovlin - Haematologica, 2024 - pmc.ncbi.nlm.nih.gov
Integration of genotypic data into clinical trial design and reporting in hereditary hemorrhagic
telangiectasia could help personalize treatment - PMC Skip to main content Here's how you …

[HTML][HTML] Effects of carbazochrome sodium sulfonate combined with tranexamic acid on hemostasis and inflammation during perioperative period of total hip …

Y Luo, Y Releken, D Yang, Y Yue, Z Liu… - … & Traumatology: Surgery & …, 2022 - Elsevier
Background The hemostatic effect of tranexamic acid (TXA) combined with carbazochrome
sodium sulfonate (CSS) in total hip arthroplasty (THA) has not been determined. Therefore …

Hemostatic and anti-inflammatory effects of carbazochrome sodium sulfonate in patients undergoing total knee arthroplasty: a randomized controlled trial

Y Luo, X Zhao, Y Releken, Z Yang, FX Pei… - The Journal of …, 2020 - Elsevier
Background Postoperative recovery after total knee arthroplasty (TKA) is associated with
postoperative anemia, allogeneic transfusion, and stress immune responses to surgery …

A series of novel 1H-indole-7-carbohydrazide derivatives with photoswitching and AIE properties:“On-off” fluorescence sensors for Cu2+

H Hu, J Li, L Shi, T Jing, C Zhang, C Gao, C Sun… - Journal of Molecular …, 2023 - Elsevier
In order to exploit novel fluorescent sensors with photoswitching properties, six fluorescent
molecules were synthesized via coupling 1H-indole-7-carbohydrazide and corresponding …

Correction pen as a hydrophobic/lipophobic barrier plotter integrated with paper-based chips and a mini UV-torch to implement all-in-one device for determination of …

R El-Shaheny, LA Al-Khateeb, MA El Hamd… - Analytica Chimica …, 2021 - Elsevier
The design of a cheap, simple, and handy sensing system for rapid quantitation of
pharmaceuticals becomes mandatory to ease drug development procedures, quality control …

Synthesis and Characterization of New N-acyl Hydrazone Derivatives of Carprofen as Potential Tuberculostatic Agents

IM Vlad, DC Nuță, MT Căproiu, F Dumitrașcu… - Antibiotics, 2024 - mdpi.com
N-acyl hydrazone (NAH) is recognized as a promising framework in drug design due to its
versatility, straightforward synthesis, and attractive range of biological activities, including …

Catalyst‐ and Solvent‐Free Synthesis of N‐Acylhydrazones via Solid‐State Melt Reaction

P Mayurachayakul, N Niamnont… - Asian Journal of …, 2022 - Wiley Online Library
We describe a fast, simple, and effective synthesis of N‐acylhydrazones via a solid‐state
melt reaction under catalyst‐and solvent‐free conditions. The reactions of 2‐furoic …

Carbazochrome sodium sulfonate is not effective for prevention of post-gastric endoscopic submucosal dissection bleeding: A retrospective study

K Takahashi, T Sasaki, N Ueno, K Uehara… - Surgical …, 2022 - Springer
Background Carbazochrome sodium sulfonate (CSS) is conventionally administered to
prevent post-endoscopic submucosal dissection (ESD) bleeding in many institutions, but …