[HTML][HTML] Selective substrate uptake: The role of ATP-binding cassette (ABC) importers in pathogenesis

KJ Tanaka, S Song, K Mason, HW Pinkett - Biochimica et Biophysica Acta …, 2018 - Elsevier
The uptake of nutrients, including metals, amino acids and peptides are required for many
biological processes. Pathogenic bacteria scavenge these essential nutrients from …

Lipoproteins in Gram-positive bacteria: abundance, function, fitness

MT Nguyen, M Matsuo, S Niemann… - Frontiers in …, 2020 - frontiersin.org
When one thinks of the Gram+ cell wall, the peptidoglycan (PG) scaffold in particular comes
to mind. However, the cell wall also consists of many other components, for example those …

Anatomy of an extensively drug-resistant Klebsiella pneumoniae outbreak in Tuscany, Italy

MJ Martin, BW Corey, F Sannio… - Proceedings of the …, 2021 - National Acad Sciences
A protracted outbreak of New Delhi metallo-β-lactamase (NDM)–producing carbapenem-
resistant Klebsiella pneumoniae started in Tuscany, Italy, in November 2018 and continued …

[HTML][HTML] Exploration of bacterial bottlenecks and Streptococcus pneumoniae pathogenesis by CRISPRi-Seq

X Liu, JM Kimmey, L Matarazzo, V de Bakker… - Cell Host & Microbe, 2021 - cell.com
Streptococcus pneumoniae is an opportunistic human pathogen that causes invasive
diseases, including pneumonia, with greater health risks upon influenza A virus (IAV) co …

Predictive computational phenotyping and biomarker discovery using reference-free genome comparisons

A Drouin, S Giguère, M Déraspe, M Marchand, M Tyers… - BMC genomics, 2016 - Springer
Background The identification of genomic biomarkers is a key step towards improving
diagnostic tests and therapies. We present a reference-free method for this task that relies …

High-resolution analysis of the pneumococcal transcriptome under a wide range of infection-relevant conditions

R Aprianto, J Slager, S Holsappel… - Nucleic acids …, 2018 - academic.oup.com
Streptococcus pneumoniae is an opportunistic human pathogen that typically colonizes the
nasopharyngeal passage and causes lethal disease in other host niches, such as the lung …

Prophages and satellite prophages are widespread in Streptococcus and may play a role in pneumococcal pathogenesis

R Rezaei Javan, E Ramos-Sevillano, A Akter… - Nature …, 2019 - nature.com
Prophages (viral genomes integrated within a host bacterial genome) can confer various
phenotypic traits to their hosts, such as enhanced pathogenicity. Here we analyse> 1300 …

In vivo transcriptomes of Streptococcus suis reveal genes required for niche-specific adaptation and pathogenesis

J Arenas, R Bossers-De Vries, J Harders-Westerveen… - Virulence, 2019 - Taylor & Francis
Streptococcus suis is a Gram-positive bacterium and a zoonotic pathogen residing in the
nasopharynx or the gastrointestinal tract of pigs with a potential of causing life-threatening …

A spectrum of CodY activities drives metabolic reorganization and virulence gene expression in Staphylococcus aureus

NR Waters, DJ Samuels, RK Behera… - Molecular …, 2016 - Wiley Online Library
The global regulator CodY controls the expression of dozens of metabolism and virulence
genes in the opportunistic pathogen Staphylococcus aureus in response to the availability of …

[HTML][HTML] Human milk oligosaccharides and non-digestible carbohydrates reduce pathogen adhesion to intestinal epithelial cells by decoy effects or by attenuating …

C Kong, A de Jong, BJ de Haan, J Kok… - Food Research …, 2022 - Elsevier
This work investigated the effects of different chemical structures of human milk
oligosaccharides (hMOs) and non-digestible carbohydrates (NDCs) on pathogen adhesion …