Numerous observational studies have suggested that there is a correlation between the
level of serum vitamin D and MS risk and disease activity. To explore this hypothesis, a …

African Americans have higher incidence of, and mortality from, many health-related
problems than European Americans. They also have a 15 to 20-fold higher prevalence of …

Multiple sclerosis (MS) is the most frequently seen demyelinating disease, with a prevalence
that varies considerably, from high levels in North America and Europe (> 100/100,000 …

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system
(CNS) affecting young people and leading to demyelination and neurodegeneration. The …

Both 25-autoimmunity and (25 (OH) D: calcifediol) and its active form, 1, 25-dihydroxyvitamin
D (1, 25 (OH) 2D: calcitriol), play critical roles in protecting humans from invasive pathogens …

It is widely known that vitamin D receptors have been found in neurons and glial cells, and
their highest expression is in the hippocampus, hypothalamus, thalamus and subcortical …

Vitamin D deficiency has been associated with the risk of multiple sclerosis, disease activity
and progression. Results from in vitro experiments, animal models and analysis of human …

Multiple sclerosis (MS) is an autoimmune disease affecting the central nervous system
(CNS), resulting from the interaction among genetic, epigenetic, and environmental factors …

Background A female/male (F/M) ratio increase over time in multiple sclerosis (MS) patients
was demonstrated in many countries around the world. So far, a direct comparison of sex …

Vitamin D research has gained increased attention in recent times due to its roles beyond
bone health and calcium homeostasis, such as immunomodulation. In some parts of the …