Blood-based biomarkers for Alzheimer disease: mapping the road to the clinic

H Hampel, SE O'Bryant, JL Molinuevo… - Nature Reviews …, 2018 - nature.com
Biomarker discovery and development for clinical research, diagnostics and therapy
monitoring in clinical trials have advanced rapidly in key areas of medicine—most notably …

Big data for health

J Andreu-Perez, CCY Poon… - IEEE journal of …, 2015 - ieeexplore.ieee.org
This paper provides an overview of recent developments in big data in the context of
biomedical and health informatics. It outlines the key characteristics of big data and how …

Bias and class imbalance in oncologic data—towards inclusive and transferrable AI in large scale oncology data sets

E Tasci, Y Zhuge, K Camphausen, AV Krauze - Cancers, 2022 - mdpi.com
Simple Summary Large-scale medical data carries significant areas of underrepresentation
and bias at all levels: clinical, biological, and management. Resulting data sets and outcome …

Feature selection approaches for predictive modelling of groundwater nitrate pollution: An evaluation of filters, embedded and wrapper methods

VF Rodriguez-Galiano, JA Luque-Espinar… - Science of the total …, 2018 - Elsevier
Recognising the various sources of nitrate pollution and understanding system dynamics
are fundamental to tackle groundwater quality problems. A comprehensive GIS database of …

A review of ensemble methods in bioinformatics

P Yang, Y Hwa Yang, BB Zhou… - Current …, 2010 - ingentaconnect.com
Ensemble learning is an intensively studied technique in machine learning and pattern
recognition. Recent work in computational biology has seen an increasing use of ensemble …

The role of AI technology in prediction, diagnosis and treatment of colorectal cancer

C Yu, EJ Helwig - Artificial intelligence review, 2022 - Springer
Artificial intelligence (AI) is a fascinating new technology that incorporates machine learning
and neural networks to improve existing technology or create new ones. Potential …

Early diagnosis of complex diseases by molecular biomarkers, network biomarkers, and dynamical network biomarkers

R Liu, X Wang, K Aihara, L Chen - Medicinal research reviews, 2014 - Wiley Online Library
Many studies have been carried out for early diagnosis of complex diseases by finding
accurate and robust biomarkers specific to respective diseases. In particular, recent rapid …

Systems medicine: the future of medical genomics and healthcare

C Auffray, Z Chen, L Hood - Genome medicine, 2009 - Springer
High-throughput technologies for DNA sequencing and for analyses of transcriptomes,
proteomes and metabolomes have provided the foundations for deciphering the structure …

Local-learning-based feature selection for high-dimensional data analysis

Y Sun, S Todorovic, S Goodison - IEEE transactions on pattern …, 2009 - ieeexplore.ieee.org
This paper considers feature selection for data classification in the presence of a huge
number of irrelevant features. We propose a new feature-selection algorithm that addresses …

Stable feature selection for biomarker discovery

Z He, W Yu - Computational biology and chemistry, 2010 - Elsevier
Feature selection techniques have been used as the workhorse in biomarker discovery
applications for a long time. Surprisingly, the stability of feature selection with respect to …