Tracking moment-to-moment change in input and detecting change sufficient to require
altering behavior is crucial to survival. Here, we discuss how the brain evaluates change …

Although the generation of movements is a fundamental function of the nervous system, the
underlying neural principles remain unclear. As flexor and extensor muscle activities …

Human imaging studies have shown that spontaneous brain activity exhibits stereotypic
spatiotemporal reorganization in awake, conscious conditions with respect to minimally …

Dynamic excitatory-inhibitory (EI) balance is a paradigmatic mechanism invoked to explain
the irregular low firing activity observed in the cortex. However, we will show that the EI …

Objective. Flexible implantable electrodes enable months-long stable recording of single-
unit signals from rat brains. Despite extensive efforts in the development of flexible probes …

How dynamic interactions between nervous system regions in mammals performs online
motor control remains an unsolved problem. In this paper, we show that feedback control is …

Targeting specific subtypes of interneurons in the spinal cord is primarily restricted to a small
group of genetic model animals. Since the development of new transgenic model animals …

During the generation of rhythmic movements, most spinal neurons receive an oscillatory
synaptic drive. The neuronal architecture underlying this drive is unknown, and the …

Although the activity from the dentate gyrus is known to have strong connections with other
hippocampal layers, the functionality of these connections, that is, the degree to which it …

Central pattern generators are circuits generating rhythmic movements, such as walking.
The majority of existing computational models of these circuits produce antagonistic output …