Four‐dimensional flow MRI for quantitative assessment of cerebrospinal fluid dynamics: Status and opportunities

LA Rivera‐Rivera, T Vikner, L Eisenmenger… - NMR in …, 2024 - Wiley Online Library
Neurological disorders can manifest with altered neurofluid dynamics in different
compartments of the central nervous system. These include alterations in cerebral blood …

Diffusion magnetic resonance imaging of cerebrospinal fluid dynamics: Current techniques and future advancements

AM Wright, YC Wu, L Feng, Q Wen - NMR in Biomedicine, 2024 - Wiley Online Library
Cerebrospinal fluid (CSF) plays a critical role in metabolic waste clearance from the brain,
requiring its circulation throughout various brain pathways, including the ventricular system …

A critical guide to the automated quantification of perivascular spaces in magnetic resonance imaging

W Pham, M Lynch, G Spitz, T O'Brien… - Frontiers in …, 2022 - frontiersin.org
The glymphatic system is responsible for waste clearance in the brain. It is comprised of
perivascular spaces (PVS) that surround penetrating blood vessels. These spaces are filled …

Glymphatic imaging in pediatrics

X Li, Z Lin, C Liu, R Bai, D Wu… - Journal of Magnetic …, 2024 - Wiley Online Library
The glymphatic system, which facilitates cerebrospinal fluid (CSF) flow through the brain
parenchyma, is important for brain development and waste clearance. Advances in imaging …

Machine Learning–Based Perivascular Space Volumetry in Alzheimer Disease

K Deike, A Decker, P Scheyhing, J Harten… - Investigative …, 2024 - journals.lww.com
Objectives Impaired perivascular clearance has been suggested as a contributing factor to
the pathogenesis of Alzheimer disease (AD). However, it remains unresolved when the …

[HTML][HTML] Effects of sleep on brain perivascular space in a cognitively healthy population

NC Shih, G Barisano, KD Lincoln, WJ Mack… - Sleep Medicine, 2023 - Elsevier
The magnetic resonance imaging (MRI) visible perivascular space (PVS) reportedly clears
amyloid-β and metabolic waste during sleep. Previous studies reported an association …

Role of the glymphatic system and perivascular spaces as a potential biomarker for post‐stroke epilepsy

G Hlauschek, JP Nicolo, B Sinclair, M Law… - Epilepsia …, 2024 - Wiley Online Library
Stroke is one of the most common causes of acquired epilepsy, which can also result in
disability and increased mortality rates particularly in elderly patients. No preventive …

Automatic Quantification of Enlarged Perivascular Space in Patients With Traumatic Brain Injury Using Super-Resolution of T2-Weighted Images

J Zhuo, P Raghavan, M Shao, S Roys… - Journal of …, 2024 - liebertpub.com
The perivascular space (PVS) is important to brain waste clearance and brain metabolic
homeostasis. Enlarged PVS (ePVS) becomes visible on magnetic resonance imaging (MRI) …

Rewiring of the glymphatic landscape in metabolic disorders

B Chen, D Meseguer, S Lenck, JL Thomas… - Trends in Endocrinology …, 2024 - cell.com
The incorporation of the glymphatic clearance system in the study of brain physiology aids in
the advancement of innovative diagnostic and treatment strategies for neurological …

Robust, fully-automated assessment of cerebral perivascular spaces and white matter lesions: a multicentre MRI longitudinal study of their evolution and association …

G Barisano, M Iv, J Choupan, M Hayden-Gephart… - …, 2025 - thelancet.com
Background Perivascular spaces (PVS) on brain MRI are surrogates for small parenchymal
blood vessels and their perivascular compartment, and may relate to brain health. However …