Circular RNAs (circRNAs) are covalently closed, endogenous biomolecules in eukaryotes
with tissue-specific and cell-specific expression patterns, whose biogenesis is regulated by …

Circular RNAs (circRNAs) are closed long non-coding RNAs, in which the 5'and 3'termini
are covalently linked by back-splicing of exons from a single pre-mRNA. Emerging evidence …

Recently, circular RNAs (circRNAs) have appealed to a growing interest due to their
abundant expression and potential functions in cancer development. The most biological …

X inactivation represents a complex multi-layer epigenetic mechanism that profoundly
modifies chromatin composition and structure of one X chromosome in females. The …

Hematopoietic stem cells differentiate into a broad range of specialized blood cells. This
process is tightly regulated and depends on transcription factors, micro-RNAs, and long non …

Background Disappointing clinical efficacy of standard treatment has been proven in
refractory metastatic osteosarcoma, and the emerging anti-angiogenic regimens are still in …

The scarcity of embryonic/foetal material as a resource for direct study means that there is
still limited understanding of human retina development. Here, we present an integrated …

Multiple sclerosis (MS) is an inflammatory, demyelinating disease of the central nervous
system with a modest concordance rate in monozygotic twins, which strongly argues for …

Circular RNAs (circRNAs) are a large class of covalently closed RNA molecules originating
by a process called back-splicing. CircRNAs are emerging as functional RNAs involved in …

Circular RNAs are covalently closed and non-coding in eukaryotes, which have tissue-
specific and temporal-specific expression patterns whose biogenesis is regulated by …