The prevalence and incidence of NAFLD worldwide: a systematic review and meta-analysis

K Riazi, H Azhari, JH Charette… - The lancet …, 2022 - thelancet.com
Background Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease
worldwide and the leading cause of liver-related morbidity and mortality. We aimed to …

The intricate relationship between type 2 diabetes mellitus (T2DM), insulin resistance (IR), and nonalcoholic fatty liver disease (NAFLD)

DM Tanase, EM Gosav, CF Costea… - Journal of diabetes …, 2020 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes mellitus (T2DM) remain as one
of the most global problematic metabolic diseases with rapidly increasing prevalence and …

[HTML][HTML] Non-alcoholic fatty liver disease: A patient guideline

SM Francque, G Marchesini, A Kautz, M Walmsley… - JHEP reports, 2021 - Elsevier
This patient guideline is intended for all patients at risk of or living with non-alcoholic fatty
liver disease (NAFLD). NAFLD is the most frequent chronic liver disease worldwide and …

Nonalcoholic steatohepatitis: a review

AC Sheka, O Adeyi, J Thompson, B Hameed… - Jama, 2020 - jamanetwork.com
Importance Nonalcoholic steatohepatitis (NASH) is the inflammatory subtype of nonalcoholic
fatty liver disease (NAFLD) and is associated with disease progression, development of …

Treatments for NAFLD: state of art

A Mantovani, A Dalbeni - International journal of molecular sciences, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is to date the most common chronic liver disease
in clinical practice and, consequently, a major health problem worldwide. It affects …

Oxidative stress in non-alcoholic fatty liver disease. An updated mini review

AP Delli Bovi, F Marciano, C Mandato, MA Siano… - Frontiers in …, 2021 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) is a challenging disease caused by multiple
factors, which may partly explain why it remains still orphan of an adequate therapeutic …

[HTML][HTML] Noninvasive evaluation of nonalcoholic fatty liver disease: Current evidence and practice

JH Zhou, JJ Cai, ZG She, HL Li - World journal of gastroenterology, 2019 - ncbi.nlm.nih.gov
With the increasing number of individuals with diabetes and obesity, nonalcoholic fatty liver
disease (NAFLD) is becoming increasingly prevalent, affecting one-quarter of adults …

[HTML][HTML] Oxidative stress in non-alcoholic fatty liver disease. An updated mini review

APD Bovi, F Marciano, C Mandato, MA Siano… - Frontiers in …, 2021 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD) is a challenging disease caused by multiple
factors, which may partly explain why it remains still orphan of an adequate therapeutic …

Macrophages in the aging liver and age-related liver disease

EC Stahl, MJ Haschak, B Popovic… - Frontiers in …, 2018 - frontiersin.org
The number of individuals aged 65 or older is projected to increase globally from 524 million
in 2010 to nearly 1. 5 billion in 2050. Aged individuals are particularly at risk for developing …

Human biomimetic liver microphysiology systems in drug development and precision medicine

A Gough, A Soto-Gutierrez, L Vernetti… - Nature reviews …, 2021 - nature.com
Microphysiology systems (MPS), also called organs-on-chips and tissue chips, are
miniaturized functional units of organs constructed with multiple cell types under a variety of …