Evolutionary pathways and trajectories in antibiotic resistance
Evolution is the hallmark of life. Descriptions of the evolution of microorganisms have
provided a wealth of information, but knowledge regarding “what happened” has precluded …
provided a wealth of information, but knowledge regarding “what happened” has precluded …
Horizontal gene transfer in the human gastrointestinal tract: potential spread of antibiotic resistance genes
JR Huddleston - Infection and drug resistance, 2014 - Taylor & Francis
Bacterial infections are becoming increasingly difficult to treat due to widespread antibiotic
resistance among pathogens. This review aims to give an overview of the major horizontal …
resistance among pathogens. This review aims to give an overview of the major horizontal …
RDP4: Detection and analysis of recombination patterns in virus genomes
RDP4 is the latest version of recombination detection program (RDP), a Windows computer
program that implements an extensive array of methods for detecting and visualising …
program that implements an extensive array of methods for detecting and visualising …
Co-occurrence of antibiotic and metal resistance genes revealed in complete genome collection
The high frequency of antibiotic resistance is a global public health concern. More seriously,
widespread metal pressure in the environment may facilitate the proliferation of antibiotic …
widespread metal pressure in the environment may facilitate the proliferation of antibiotic …
A phylogenomic view of ecological specialization in the Lachnospiraceae, a family of digestive tract-associated bacteria
Several bacterial families are known to be highly abundant within the human microbiome,
but their ecological roles and evolutionary histories have yet to be investigated in depth. One …
but their ecological roles and evolutionary histories have yet to be investigated in depth. One …
Timing the evolution of antioxidant enzymes in cyanobacteria
The ancestors of cyanobacteria generated Earth's first biogenic molecular oxygen, but how
they dealt with oxidative stress remains unconstrained. Here we investigate when …
they dealt with oxidative stress remains unconstrained. Here we investigate when …
De novo assembly and genotyping of variants using colored de Bruijn graphs
Detecting genetic variants that are highly divergent from a reference sequence remains a
major challenge in genome sequencing. We introduce de novo assembly algorithms using …
major challenge in genome sequencing. We introduce de novo assembly algorithms using …
[HTML][HTML] Ecological and evolutionary forces shaping microbial diversity in the human intestine
RE Ley, DA Peterson, JI Gordon - Cell, 2006 - cell.com
The human gut is populated with as many as 100 trillion cells, whose collective genome, the
microbiome, is a reflection of evolutionary selection pressures acting at the level of the host …
microbiome, is a reflection of evolutionary selection pressures acting at the level of the host …
[图书][B] Processes of life: Essays in the philosophy of biology
J Dupré - 2012 - books.google.com
John Dupré explores recent revolutionary developments in biology and considers their
relevance for our understanding of human nature and human society. Epigenetics and …
relevance for our understanding of human nature and human society. Epigenetics and …
Bacterial genome instability
E Darmon, DRF Leach - Microbiology and Molecular Biology …, 2014 - Am Soc Microbiol
Bacterial genomes are remarkably stable from one generation to the next but are plastic on
an evolutionary time scale, substantially shaped by horizontal gene transfer, genome …
an evolutionary time scale, substantially shaped by horizontal gene transfer, genome …