M Ruscica, N Ferri, M Banach, CR Sirtori… - Cardiovascular …, 2022 - academic.oup.com
Abstract Treatment with statins, inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A reductase, has proven beneficial preventive effects on cardiovascular events. However …
CA German, JK Liao - Archives of Toxicology, 2023 - Springer
Statins represent the cornerstone of pharmacotherapy for the prevention of atherosclerotic cardiovascular disease. These medications not only reduce low-density lipoprotein …
RM Turner, M Pirmohamed - Journal of clinical medicine, 2019 - mdpi.com
Statins are a cornerstone in the pharmacological prevention of cardiovascular disease. Although generally well tolerated, a small subset of patients experience statin-related …
R Cacabelos, N Cacabelos, JC Carril - Expert Review of Clinical …, 2019 - Taylor & Francis
ABSTRACT Introduction: Adverse drug reactions (ADRs) are a major health concern worldwide. There are multiple causes of ADRs, some of which are preventable …
Z Wu, R Wu, X Li, X Wang, X Tang, K Tan, M Wan… - Small, 2022 - Wiley Online Library
Most of the current non‐pharmacological treatment strategies for atherosclerosis (AS) suffer from poor penetration into the plaque and only aim at a certain factor in its formation …
Y Zhang, C Liao, M Abudusaimaiti… - Advanced Functional …, 2024 - Wiley Online Library
Spatial and temporal precisely control of direction and speed is crucial for nanomotors to enable complex operations and applications in microsurgery, drug delivery, isolation of …
Statins, a class of lipid-lowering medications, have been a keystone treatment in cardiovascular health. However, adverse effects associated with statin use impact patient …
V Rollinson, R Turner, M Pirmohamed - Genes, 2020 - mdpi.com
Most of the prescribing and dispensing of medicines happens in primary care. Pharmacogenomics (PGx) is the study and clinical application of the role of genetic variation …
LR Brunham, S Baker, A Mammen… - Cardiovascular …, 2018 - academic.oup.com
Statin therapy reduces cardiovascular events in patients with, or at risk of, atherosclerotic cardiovascular disease. However, statins are underutilized in patients for whom they are …