The biofilm life cycle: expanding the conceptual model of biofilm formation

K Sauer, P Stoodley, DM Goeres… - Nature Reviews …, 2022 - nature.com
Bacterial biofilms are often defined as communities of surface-attached bacteria and are
typically depicted with a classic mushroom-shaped structure characteristic of Pseudomonas …

Tolerance and resistance of microbial biofilms

O Ciofu, C Moser, PØ Jensen, N Høiby - Nature Reviews Microbiology, 2022 - nature.com
Chronic infections caused by microbial biofilms represent an important clinical challenge.
The recalcitrance of microbial biofilms to antimicrobials and to the immune system is a major …

Bacterial biofilm and its role in the pathogenesis of disease

LK Vestby, T Grønseth, R Simm, LL Nesse - Antibiotics, 2020 - mdpi.com
Recognition of the fact that bacterial biofilm may play a role in the pathogenesis of disease
has led to an increased focus on identifying diseases that may be biofilm-related. Biofilm …

[HTML][HTML] Tolerance and resistance of Pseudomonas aeruginosa biofilms to antimicrobial agents—how P. aeruginosa can escape antibiotics

O Ciofu, T Tolker-Nielsen - Frontiers in microbiology, 2019 - frontiersin.org
Pseudomonas aeruginosa is one of the six bacterial pathogens, Enterococcus faecium,
Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas …

Targeting microbial biofilms: current and prospective therapeutic strategies

H Koo, RN Allan, RP Howlin, P Stoodley… - Nature Reviews …, 2017 - nature.com
Biofilm formation is a key virulence factor for a wide range of microorganisms that cause
chronic infections. The multifactorial nature of biofilm development and drug tolerance …

Biofilm exacerbates antibiotic resistance: Is this a current oversight in antimicrobial stewardship?

P Bowler, C Murphy, R Wolcott - Antimicrobial Resistance & Infection …, 2020 - Springer
Objective To raise awareness of the role of environmental biofilm in the emergence and
spread of antibiotic resistance and its consideration in antimicrobial stewardship …

Nanomaterials for wound healing and infection control

MM Mihai, MB Dima, B Dima, AM Holban - Materials, 2019 - mdpi.com
Wound healing has been intensely studied in order to develop an “ideal” technique that
achieves expeditious recovery and reduces scarring to the minimum, thus ensuring function …

[HTML][HTML] Biofilms by bacterial human pathogens: Clinical relevance-development, composition and regulation-therapeutical strategies

A Schulze, F Mitterer, JP Pombo, S Schild - Microbial Cell, 2021 - ncbi.nlm.nih.gov
Notably, bacterial biofilm formation is increasingly recognized as a passive virulence factor
facilitating many infectious disease processes. In this review we will focus on bacterial …

Biofilms in chronic wounds: pathogenesis and diagnosis

YK Wu, NC Cheng, CM Cheng - Trends in biotechnology, 2019 - cell.com
Chronic non-healing wounds have become a major worldwide healthcare burden. The
impact of biofilms on chronic wound infection is well established. Despite increasing …

The prevalence of biofilms in chronic wounds: a systematic review and meta-analysis of published data

M Malone, T Bjarnsholt, AJ McBain… - Journal of wound …, 2017 - magonlinelibrary.com
The presence of biofilms in chronic non-healing wounds, has been identified through in vitro
model and in vivo animal data. However, human chronic wound studies are under …