The incidence of acute pancreatitis continues to increase worldwide, and it is one of the
most common gastrointestinal causes for hospital admission in the USA. In the past decade …

Neutrophils are the most abundant leukocytes in the circulation, and have been regarded as
first line of defense in the innate arm of the immune system. They capture and destroy …

In severe cases of coronavirus disease 2019 (COVID-19), viral pneumonia progresses to
respiratory failure. Neutrophil extracellular traps (NETs) are extracellular webs of chromatin …

Metabolic rewiring and epigenetic remodeling, which are closely linked and reciprocally
regulate each other, are among the well-known cancer hallmarks. Recent evidence …

Acute pancreatitis may be associated with both local and systemic complications. Systemic
injury manifests in the form of organ failure, which is seen in approximately 20% of all cases …

Neutrophils, the most abundant type of leukocytes in blood, can form neutrophil extracellular
traps (NETs). These are pathogen-trapping structures generated by expulsion of the …

Background The endoglycosidase heparanase which degrades heparan sulfate
proteoglycans, exerts a pro-inflammatory mediator in various inflammatory disorders …

Severe acute pancreatitis (SAP) is an inflammatory disease of the pancreas accompanied
by tissue injury and necrosis. It not only affects the pancreas but also triggers a systemic …

The ongoing outbreak of Coronavirus disease 2019 infection achieved pandemic status on
March 11, 2020. As of September 8, 2020 it has caused over 890,000 mortalities world-wide …

Since the discovery of the first trypsinogen mutation in families with hereditary pancreatitis,
pancreatic genetics has made rapid progress. The identification of mutations in genes …