Physiological functions of the cellular prion protein
AR Castle, AC Gill - Frontiers in molecular biosciences, 2017 - frontiersin.org
The prion protein, PrPC, is a small, cell-surface glycoprotein notable primarily for its critical
role in pathogenesis of the neurodegenerative disorders known as prion diseases. A …
role in pathogenesis of the neurodegenerative disorders known as prion diseases. A …
The cellular and pathologic prion protein
AC Gill, AR Castle - Handbook of clinical neurology, 2018 - Elsevier
The cellular prion protein, PrP C, is a small, cell surface glycoprotein with a function that is
currently somewhat ill defined. It is also the key molecule involved in the family of …
currently somewhat ill defined. It is also the key molecule involved in the family of …
Common structural traits across pathogenic mutants of the human prion protein and their implications for familial prion diseases
Human (Hu) familial prion diseases are associated with about 40 point mutations of the
gene coding for the prion protein (PrP). Most of the variants associated with these mutations …
gene coding for the prion protein (PrP). Most of the variants associated with these mutations …
Cellular prion protein offers neuroprotection in astrocytes submitted to amyloid β oligomer toxicity
CMS Marques, RN Gomes, T Pedron, BL Batista… - Molecular and Cellular …, 2023 - Springer
The cellular prion protein (PrPC), in its native conformation, performs numerous cellular and
cognitive functions in brain tissue. However, despite the cellular prion research in recent …
cognitive functions in brain tissue. However, despite the cellular prion research in recent …
Scrapie incidence and PRNP polymorphisms: rare small ruminant breeds of Sicily with TSE protecting genetic reservoirs
Background Transmissible spongiform encephalopathies (TSE) are fatal neurodegenerative
diseases of several mammalian species, including humans. In Italy, the active surveillance …
diseases of several mammalian species, including humans. In Italy, the active surveillance …
Protein structure along the order–disorder continuum
Thermal fluctuations cause proteins to adopt an ensemble of conformations wherein the
relative stability of the different ensemble members is determined by the topography of the …
relative stability of the different ensemble members is determined by the topography of the …
Roles of prion proteins in mammalian development
YP Cheon, C Ryou, ŽM Svedružić - Animal Cells and Systems, 2024 - Taylor & Francis
Prion protein (PrP) is highly conserved and is expressed in most tissues in a developmental
stage-specific manner. Glycosylated cellular prion protein (PrPC) is found in most cells and …
stage-specific manner. Glycosylated cellular prion protein (PrPC) is found in most cells and …
Cellular prion protein activates Caspase 3 for apoptotic defense mechanism in astrocytes
CMS Marques, T Pedron, BL Batista… - Molecular and Cellular …, 2021 - Springer
The cellular prion protein (PrP C) is anchored in the plasma membrane of cells, and it is
highly present in cells of brain tissue, exerting numerous cellular and cognitive functions …
highly present in cells of brain tissue, exerting numerous cellular and cognitive functions …
[图书][B] Foodborne viral pathogens
Viral transmission through contaminated food and water claims hundreds of thousands of
lives every year, particularly affecting children in developing nations. Foodborne viral …
lives every year, particularly affecting children in developing nations. Foodborne viral …
Photocatalytic inactivation of viruses and prions: Multilevel approach with other disinfectants
T Onodera, K Sugiura, M Haritani, T Suzuki… - Applied …, 2022 - mdpi.com
Ag, Cu, Zn, Ti, and Au nanoparticles show enhanced photocatalytic properties. Efficient
indoor disinfection strategies are imperative to manage the severe acute respiratory …
indoor disinfection strategies are imperative to manage the severe acute respiratory …