Circadian rhythms are internal manifestations of the solar day that permit adaptations to
predictable environmental temporal changes. These~ 24-h rhythms are controlled by …

We summarize evidence supporting contemporary pharmacological treatment of phases of
BD, including: mania, depression, and long-term recurrences, emphasizing findings from …

A comprehensive resource for mental health professionals—now in a fully revised and
updated tenth edition. The Handbook of Clinical Psychopharmacology for Therapists is the …

Lithium (Li+) is a first option treatment for adult acute episodes of Bipolar Disorder (BD) and
for the prophylaxis of new depressed or manic episodes. It is also the preferred choice as …

In this paper, we propose that lithium may exert its therapeutic effect in bipolar disorder by
acting on insulin signaling pathways. Specifically, we assess the importance of the …

Over the last six decades, lithium has been considered the gold standard treatment for the
long-term management of bipolar disorder due to its efficacy in preventing both manic and …

Emotion dysregulation (ED) describes a difficulty with the modulation of which emotions are
felt, as well as when and how these emotions are experienced or expressed. It is a focal …

Background After chemotherapy, many cancer survivors suffer from long-lasting cognitive
impairment, colloquially known as “chemobrain.” However, the trajectories of cognitive …

Epidemiological, clinical, and basic research over the past thirty years have described the
benefits of estrogen on cognition, mood, and brain health. Less is known about tamoxifen, a …

Zinc finger proteins are one of the most abundant families of proteins and present a wide
range of structures and functions. The structural zinc ion provides the correct conformation to …