Objective: This meta-analysis was designed to explore the association between the systemic
immune–inflammation index (SII) and the therapeutic effect of immune checkpoint inhibitors …

The production and release of tumor-derived small extracellular vesicles (TDSEVs) from
cancerous cells play a pivotal role in the propagation of cancer, through genetic and …

Blood-based biomarkers reflect systemic inflammation status and have prognostic and
predictive value in solid malignancies. As a recently defined biomarker, Pan-Immune …

Chemotherapy-induced thrombocytopenia (CIT) is a common complication of the treatment
of non-hematologic malignancies. Many patient-related variables (eg, age, tumor type …

Tumor metastasis contributes to the low overall survival of tumor patients, while transforming
growth factor-β (TGFβ) has been recognized as a prominently promoting factor in the …

Surgical resection continues to be the mainstay treatment for solid cancers even though
chemotherapy and immunotherapy have significantly improved patient overall survival and …

Oxidative stress (OS) is a chemical imbalance between an oxidant and an antioxidant,
causing damage to redox signaling and control or causing molecular damage. Unbalanced …

Platelets are hematopoietic cells whose main function has for a long time been considered
to be the maintenance of vascular integrity. They have an essential role in the hemostatic …

Simple Summary Spine metastases are a common life-threatening complication of
advanced-stage malignancies and often result in poor prognosis. Symptomatic spine …

The Golgi apparatus plays a central role in normal cell physiology by promoting cell survival,
facilitating proliferation, and enabling cell-cell communication and migration. These roles …