Acute graft-versus-host disease

F Malard, E Holler, BM Sandmaier, H Huang… - Nature Reviews …, 2023 - nature.com
Acute graft-versus-host disease (GVHD) is a common immune complication that can occur
after allogeneic haematopoietic cell transplantation (alloHCT). Acute GVHD is a major …

Allogeneic stem cell transplantation for acute myeloid leukemia: who, when, and how?

J Loke, R Buka, C Craddock - Frontiers in immunology, 2021 - frontiersin.org
Although the majority of patients with acute myeloid leukemia (AML) treated with intensive
chemotherapy achieve a complete remission (CR), many are destined to relapse if treated …

Impact of immune modulation with anti–T-cell antibodies on the outcome of reduced-intensity allogeneic hematopoietic stem cell transplantation for hematologic …

RJ Soiffer, J LeRademacher, V Ho… - Blood, The Journal …, 2011 - ashpublications.org
The success of reduced intensity conditioning (RIC) transplantation is largely dependent on
alloimmune effects. It is critical to determine whether immune modulation with anti–T-cell …

Results of a HOVON/SAKK donor versus no-donor analysis of myeloablative HLA-identical sibling stem cell transplantation in first remission acute myeloid leukemia in …

JJ Cornelissen, WLJ Van Putten, LF Verdonck… - Blood, 2007 - ashpublications.org
Abstract The Dutch-Belgian Hemato-Oncology Cooperative Group and the Swiss Group for
Clinical Cancer Research (HOVON-SAKK) collaborative study group evaluated outcome of …

Treatment, risk factors, and outcome of adults with relapsed AML after reduced intensity conditioning for allogeneic stem cell transplantation

C Schmid, M Labopin, A Nagler… - Blood, The Journal …, 2012 - ashpublications.org
Because information on management and outcome of AML relapse after allogeneic
hematopoietic stem cell transplantation (HSCT) with reduced intensity conditioning (RIC) is …

Adoptive transfer of cytomegalovirus-specific CTL to stem cell transplant patients after selection by HLA–peptide tetramers

M Cobbold, N Khan, B Pourgheysari, S Tauro… - The Journal of …, 2005 - rupress.org
Stem cell transplantation is used widely in the management of a range of diseases of the
hemopoietic system. Patients are immunosuppressed profoundly in the early posttransplant …

Graft-versus-host disease after nonmyeloablative versus conventional hematopoietic stem cell transplantation

M Mielcarek, PJ Martin, W Leisenring, MED Flowers… - Blood, 2003 - ashpublications.org
It is unknown whether the severity, timing, and quality of graft-versus-host disease (GVHD)
may be different after nonmyeloablative as compared with myeloablative hematopoietic …

Long-term survival in refractory acute myeloid leukemia after sequential treatment with chemotherapy and reduced-intensity conditioning for allogeneic stem cell …

C Schmid, M Schleuning, R Schwerdtfeger… - Blood, 2006 - ashpublications.org
A sequential regimen of chemotherapy, reduced-intensity conditioning (RIC) for allogeneic
stem cell transplantation (SCT), and prophylactic donor lymphocyte transfusion (pDLT) was …

Comorbidity and disease status–based risk stratification of outcomes among patients with acute myeloid leukemia or myelodysplasia receiving allogeneic …

ML Sorror, BM Sandmaier, BE Storer… - Journal of Clinical …, 2007 - ascopubs.org
Purpose Retrospective studies have shown similar survival among patients with acute
myeloid leukemia (AML) and myelodysplasia (MDS) after nonmyeloablative compared with …

Umbilical cord blood transplantation after nonmyeloablative conditioning: impact on transplantation outcomes in 110 adults with hematologic disease

CG Brunstein, JN Barker, DJ Weisdorf… - Blood, The Journal …, 2007 - ashpublications.org
We evaluated the efficacy of umbilical cord blood (UCB) in the setting of a nonmyeloablative
regimen consisting of fludarabine (200 mg/m2), cyclophosphamide (50 mg/kg), and a single …