Medication-related osteonecrosis of the jaw (MRONJ) is a potentially severe adverse event
affecting patients with cancer and patients with osteoporosis who have been treated with …

Objective This study was performed to determine whether the results of prevailing in vivo
and in vitro studies offer a reliable model for investigation of medication-related …

Denosumab and zoledronic acid are potent antiresorptives. In this study in patients pre-
treated with zoledronic acid, denosumab achieved similar increases with zoledronic acid in …

Purpose Osteonecrosis of the jaw after tooth extraction is a major complication in patients
using bisphosphonates (BPs) for bone lesions, such as for the treatment of osteoporosis …

Objective To investigate the preventive effect of locally applied sodium bicarbonate on
bisphosphonate-related osteonecrosis of the jaw (BRONJ). Study Design Thirty-six Sprague …

Objectives This study aimed to investigate the therapeutic effect of different doses of
teriparatide (TPTD) on bisphosphonate‐related osteonecrosis of the jaw (BRONJ). Materials …

Background We determined whether serum levels of Receptor Activator for Nuclear Factor κ
B Ligand (RANKL), Osteoprotegerin (OPG), and the RANKL/OPG ratio could be useful …

The pathogenesis of bisphosphonate-related osteonecrosis of the jaw (BRONJ) is highly
controversial. We have previously reported the development of osteonecrosis by periodontal …

Objective This study aims to evaluate bone repair and the development of the medication
related osteonecrosis of the jaw (MRONJ) associated with the use of zoledronic acid in …

Objectives Nitrogen-containing bisphosphonates induce osteonecrosis mostly in the jaw
and less frequently in other bones. Because of the crucial role of periosteal perfusion in …