Lung cancer is the primary cause of mortality in the United States and around the globe.
Therapeutic options for lung cancer treatment include surgery, radiation therapy …

T cell engineering has changed the landscape of cancer immunotherapy. Chimeric antigen
receptor T cells have demonstrated a remarkable efficacy in the treatment of B cell …

Hepatocellular carcinoma (HCC) is one of the most common solid malignancies worldwide.
A large proportion of patients with HCC are diagnosed at advanced stages and are only …

There have been many ups and downs since the introduction of gene therapy as a
therapeutic modality for diseases. However, the journey of gene therapy has reached a …

Osteosarcoma, with poor survival after metastasis, is considered the most common primary
bone cancer in adolescents. Notwithstanding the efforts of researchers, its five-year survival …

Breast cancer is the most commonly diagnosed cancer (estimated 2.3 million new cases in
2020) and the leading cause of cancer death (estimated 685,000 deaths in 2020) in women …

During the course of tumorigenesis and subsequent metastasis, malignant cells gradually
diversify and become more heterogeneous. Consequently, the tumor mass might be …

Immune checkpoint inhibition and chimeric antigen receptor (CAR) T cell therapy have
demonstrated stunning clinical efficacy in many cancer types. However, most patients do not …

Endometriosis, an estrogen-dependent chronic inflammatory disease characterized by the
growth of endometrium-like tissues outside the uterine cavity, affects 10% of reproductive …

T cell receptor-engineered T cell (TCR-T) therapy is free from the limit of surface antigen
expression of the target cells, which is a potential cellular immunotherapy for cancer …