TAR DNA-binding protein 43, mostly referred to as TDP-43 (encoded by the TARDBP gene)
is strongly linked to the pathogenesis of amyotrophic lateral sclerosis (ALS) and …

Abstract RNA-binding proteins (RBPs), which are conserved proteins comprising multiple
intermediate sequences, can interact with proteins, messenger RNA (mRNA) of coding …

Cu (Cu) is essential for several biochemical pathways due to its role as a catalytic cofactor or
allosteric regulator of enzymes. Its import and distribution are tightly controlled by …

Abstract Amyotrophic Lateral Sclerosis (ALS) is a multisystemic neurodegenerative disorder,
with accumulating evidence indicating metabolic disruptions in the skeletal muscle …

The ability of terrestrial vertebrates to find food and mating partners, and to avoid predators,
relies on the detection of chemosensory information. Semiochemicals responsible for social …

Static gene expression programs have been extensively characterized in stem cells and
mature human cells. However, the dynamics of RNA isoform changes upon cell-state …

We performed scRNA-seq/snATAC-seq of skeletal muscles post sciatic nerve transection to
delineate cell type-specific patterns of gene expression/chromatin accessibility at different …

Heterogeneous nuclear ribonucleoproteins (hnRNPs) are a superfamily of RNA-binding
proteins consisting of more than 20 members. These proteins play a crucial role in various …

Glucose binding can alter protein oligomerization to enable differentiation. Here, we
demonstrate that glucose binding is a general capacity of DExD/H-box RNA helicases …

Alternative splicing (AS) is a fundamental mechanism contributing to proteome diversity, yet
its comprehensive landscape and regulatory dynamics during skeletal muscle development …