Microglia (MG) play a crucial role as the predominant myeloid cells in the central nervous
system and are commonly activated in multiple sclerosis. They perform essential functions …

Simple Summary A stroke occurs when there is a lack of blood flow to the brain. Stroke
injures the brain and can have devastating outcomes depending on the size and location of …

Synaptic dysfunction is an early mechanism in Alzheimer's disease that involves
progressively larger areas of the brain over time. However, how it starts and propagates is …

Following ischemic stroke, brain‐resident activated microglia and peripherally infiltrated
inflammatory cells create a complicated and overactivated brain immune microenvironment …

Neuroinflammation is a hallmark of many neurological diseases, including traumatic brain
injury (TBI), which is usually characterized by two pathological hallmarks: activation of …

Astrocytes‐derived extracellular vesicles (EVs) are key players in glia‐neuron
communication. However, whether EVs interact with neurons at preferential sites and how …

Cellular prion protein (PrPC) is a glycosylphosphatidylinositol (GPI)-anchored protein most
abundantly found in the outer membrane of neurons. Due to structural characteristics (a …

Stroke is a leading cause of death and disability in the world. Astrocytes are special glial
cells within the central nervous system and play important roles in mediating …

Ischemic stroke is a damaging cerebral vascular disease associated with high disability and
mortality rates worldwide. In spite of the continuous development of new diagnostic and …

Information exchange is essential for the brain, where it communicates the physiological and
pathological signals to the periphery and vice versa. Extracellular vesicles (EVs) are a …